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Cuckoo search with mutation for biclustering of microarray gene expression data
المؤلفون المشاركون
Mathaiyan, Natarajan
Rengeswaran, Balamurugan
Kandasamy, Premalatha
المصدر
The International Arab Journal of Information Technology
العدد
المجلد 14، العدد 3 (31 مايو/أيار 2017)7ص.
الناشر
تاريخ النشر
2017-05-31
دولة النشر
الأردن
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
DNA microarrays have been applied successfully in diverse research fields such as gene discovery, disease diagnosis and drug discovery.
The roles of the genes and the mechanisms of the underlying diseases can be identified using microarrays.
Biclustering is a two dimensional clustering problem, where we group the genes and samples simultaneously.
It has a great potential in detecting marker genes that are associated with certain tissues or diseases.
The proposed work finds the significant biclusters in large expression data using the Cuckoo Search with Mutation (CSM).
The cuckoo imitates it’s egg similar to host bird’s egg using a mutation operator.
Mutation is used for exploration of search space, more precisely to allow candidates to escape from local minima.
It focuses on finding maximum biclusters with lower Mean Squared Residue (MSR) and higher gene variance.
A qualitative measurement of the formed biclusters with a comparative assessment of results is provided on four benchmark gene expression dataset.
To demonstrate the effectiveness of the proposed method, the results are compared with the swarm intelligence techniques Binary Particle Swarm Optimization (BPSO), Shuffled Frog Leaping (SFL), and Cuckoo search with Levy flight (CS) algorithm.
The results show that there is significant improvement in the fitness value.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rengeswaran, Balamurugan& Mathaiyan, Natarajan& Kandasamy, Premalatha. 2017. Cuckoo search with mutation for biclustering of microarray gene expression data. The International Arab Journal of Information Technology،Vol. 14, no. 3.
https://search.emarefa.net/detail/BIM-819507
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rengeswaran, Balamurugan…[et al.]. Cuckoo search with mutation for biclustering of microarray gene expression data. The International Arab Journal of Information Technology Vol. 14, no. 3 (2017).
https://search.emarefa.net/detail/BIM-819507
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rengeswaran, Balamurugan& Mathaiyan, Natarajan& Kandasamy, Premalatha. Cuckoo search with mutation for biclustering of microarray gene expression data. The International Arab Journal of Information Technology. 2017. Vol. 14, no. 3.
https://search.emarefa.net/detail/BIM-819507
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-819507
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