Prevalence of thyroid dysfunction in patients with metabolic syndrome

العناوين الأخرى

معدل انتشار قصور الغدة الدرقية لدى الأشخاص المصابين بالمتلازمة الأيضية

المؤلفون المشاركون

Sabri, Said M.
al-Tamimi, Diya J.

المصدر

Duhok Medical Journal

الناشر

جامعة دهوك كلية الطب

تاريخ النشر

2012-12-31

دولة النشر

العراق

عدد الصفحات

9

التخصصات الرئيسية

الطب البشري

الملخص الإنجليزي

Background and Objective: The metabolic syndrome (MS) and thyroid dysfunction are independent risk factors of atherosclerotic cardiovascular disease; coexistence of the two will substantially increase cardiovascular risk.

We aim in this paper to report on patients with the metabolic syndrome a) the prevalence of thyroid dysfunction b) the association between thyroid hormones and metabolic syndrome components.

Methods: One-hundred patients who attended Duhok Diabetes Center during the period of the study and confirmed to have the metabolic syndrome were enrolled in this study.

The study was conducted between 1st November 2010 and 30th June 2011.

The diagnosis of the metabolic syndrome was based on the criteria set by the American National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III).

The anthropometric measurements were done and fasting blood samples were analyzed for free triiodothyronine (free T3), free thyroxine (free T4), thyroid stimulating hormone (TSH), lipid profile, insulin, and glucose and these values were compared with those in a control population (n = 100).

Results: The prevalence of thyroid dysfunction was significantly higher among MS patients as compared to control subjects.

Of the one-hundred patients with MS, 77% were euthyroid, 19% had subclinical hypothyroidism and 4% had overt hypothyroidism.

With respect to the control subjects, 96% were euthyroid and 4% had subclinical hypothyroidism.

Hyperthyroidism was not present in any of the participants.

Free T3 and free T4 were significantly lower in euthyroid MS patients than in the controls (P < 0.01).

Thyroid stimulating hormone (TSH) correlated positively with the number of metabolic syndrome components (P < 0.05).

Free T3 and free T4 did not correlate with metabolic syndrome components.

Conclusions: It can be concluded that metabolic syndrome patients have a higher prevalence of thyroid dysfunction which might predispose them to cardiovascular events

نوع البيانات

أوراق مؤتمرات

رقم السجل

BIM-832011

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