Anti-Mullerian hormone is a significant marker for male infertility

العناوين الأخرى

هرموناتني مولى رين كعلامة فارقة لعقم الرجال

المؤلفون المشاركون

al-Shalabi, Sajidah A.
al-Galil, Islam M.
al-Wattar, Yasir T.

المصدر

Duhok Medical Journal

الناشر

جامعة دهوك كلية الطب

تاريخ النشر

2012-12-31

دولة النشر

العراق

عدد الصفحات

6

التخصصات الرئيسية

العلوم الطبية والصيدلة والعلوم الصحية

الملخص الإنجليزي

Background & objective: Anti-Mullerian hormone is a glycoprotein that belongs to the transforming growth factor- B(TGF-B) a member of the super family of growth & differentiation factors.

It is thought to be involved in the inhibition of steroid hormone production in women of reproductive age.

We aimed to evaluate serum antiMullerian hormone (AMH) in men with normal, reduced sperm concentration and in azoospermic men as a possible clinical marker of male factor infertility.

Design Prospective study SettingPrivate clinic of Dr.

Yasir Al-Wattar and Al-Batool Teaching Hospital in Mosul.

Subjects & Methods: This study was conducted on one hundred male subjects aged less than 50 years for the period from July2011-November2011, infertile men were classified according to their sperm count into oligospermics (n=28) and azoospermics(n=47), twenty five men were normal fertile (n=25).Serum concentrations of FSH and Testosterone were measured using ELISA,serum Anti-Mullerian hormone concentrations were measured using AMH/MIS enzyme linked immunosorbant assay kit.

Results: Significant differences in serum Anti- Mullerian hormone, follicle stimulating hormone and Testosterone concentrations were found between normal, oligospermic & azoospermic men.Anti-Mullerian hormone negatively correlated with follicle stimulating hormone in oligospermic and azoospermic men and positively with testosterone in azoospermics and negatively with testosterone in oligospermics.

Conclusion: Anti-Mullerian hormone may serve as a marker of male infertility.

نوع البيانات

أوراق مؤتمرات

رقم السجل

BIM-832273

• APA
• MLA
• AMA