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Accumulation of iron oxide nanoparticle and conventional iron oxide in rat ovary and oxidative stress caused by it
المؤلفون المشاركون
Poormoosavi, Sayyidah Mahsa
Morovvati, Hasan
Varzi, Husayn Najaf Zadah
Behmanesh, Muhammad Amin
Shahryari, Ali
Muhammadian, Babak
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 20، العدد 1 (31 يناير/كانون الثاني 2018)، ص ص. 1-6، 6ص.
الناشر
تاريخ النشر
2018-01-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
6
التخصصات الرئيسية
العلوم الطبية والصيدلة والعلوم الصحية
الملخص EN
Background: Iron is one of the most essential elements of life that plays a major role in structure of the most cells of body and is potentially toxic and dangerous, because it easily participates in oxidation-reduction reactions and produces reactive oxygen species, which leads to oxidative stress; nanomaterials such as iron nanoparticles found in environmental pollution and can also be dangerous.
Objectives: The current study aimed at evaluating and comparing the effects of accumulation of conventional iron oxide and iron oxide nanoparticles in rat ovary and its relationship with serum oxidative stress.
Methods: The current experimental study was conducted on 5 groups of female rats, control, iron oxide (15 mg/kg), and iron oxide nanoparticles (5, 15, and 45 mg/kg).
All rats were treated intraperitoneally for 16 days.
Then, they were euthanized and their ovarian tissue was removed, and iron accumulation in the ovaries was measured by atomic absorption.
Malondialdehyde (MDA), carbonyl protein, thiol protein, and total antioxidant activity were also measured in rats serum samples.
Results: According to the current study findings, iron accumulation increased significantly (P = 0.046) in the group that received conventional iron oxide, as compared with the control group.
Also, the mean of total antioxidant activity (4.4 294.31 M/L) and thiol protein (3.3381.09 m/mL) showed a significant (P0.05) differences in group that received conventional iron oxide, compared with the other groups, MDA and protein carbonyl had no significant (P 0.05) difference.
Conclusions: According to the findings, conventional iron oxide particle induced more accumulation and more oxidative stress than nanoparticles.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Poormoosavi, Sayyidah Mahsa& Morovvati, Hasan& Varzi, Husayn Najaf Zadah& Behmanesh, Muhammad Amin& Shahryari, Ali& Muhammadian, Babak. 2018. Accumulation of iron oxide nanoparticle and conventional iron oxide in rat ovary and oxidative stress caused by it. Iranian Red Crescent Medical Journal،Vol. 20, no. 1, pp.1-6.
https://search.emarefa.net/detail/BIM-835992
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Poormoosavi, Sayyidah Mahsa…[et al.]. Accumulation of iron oxide nanoparticle and conventional iron oxide in rat ovary and oxidative stress caused by it. Iranian Red Crescent Medical Journal Vol. 20, no. 1 (Jan. 2018), pp.1-6.
https://search.emarefa.net/detail/BIM-835992
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Poormoosavi, Sayyidah Mahsa& Morovvati, Hasan& Varzi, Husayn Najaf Zadah& Behmanesh, Muhammad Amin& Shahryari, Ali& Muhammadian, Babak. Accumulation of iron oxide nanoparticle and conventional iron oxide in rat ovary and oxidative stress caused by it. Iranian Red Crescent Medical Journal. 2018. Vol. 20, no. 1, pp.1-6.
https://search.emarefa.net/detail/BIM-835992
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 5-6
رقم السجل
BIM-835992
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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