Outcome of different treatment regimens used in newly diagnosed ITP pediatric patients
المؤلفون المشاركون
Harun, Mirfat al-Sayyid
Habib, Nisrin Mustafa
Afifi, Rasha Abd al-Rauf Abd al-Aziz
المصدر
Egyptian Pediatric Association Gazette
العدد
المجلد 66، العدد 2 (30 يونيو/حزيران 2018)، ص ص. 39-42، 4ص.
الناشر
تاريخ النشر
2018-06-30
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الموضوعات
الملخص EN
Aim of the study: To compare the efficacy of different treatment options for newly diagnosed ITP in pediatrics.
Patients and methods: This is a retrospective observational study that reviewed data of 102 newly diagnosed ITP children.
Treatment regimens received by patients were classified into 5 types: Type I: pulse intravenous methylprednisolone followed by oral prednisolone then gradual tapering.
Type II: oral prednisolone 4 mg/kg/d 4 days.
Type III: oral prednisolone 2 mg/kg/d followed by gradual tapering.
Type IV: intravenous immune globulin (IVIG) combined with intravenous methylprednisolone.
Type V: no treatment.
Platelet counts at presentation, after 1 week, at 1 month, 3 months and 6 months from initial presentation were analyzed.
Results: Patients who received Type I, III or IV treatment showed statistically significant higher response to treatment at 1 week (96.1%, 93.3%, and 100% respectively) in comparison to those who received Type II or no treatment (Type V) in which less response was observed (58.8% and 75% respectively); (p-value = 0.
001%).
However, the overall response showed no statistically significant difference in response to treatment using different types of treatment at one month and 3 months, p-value = 0.086 and 0.335 respectively.
When we evaluated the response overtime of each line of treatment at 3 months, Type I showed a statistically significant response (p = 0.009) with the biggest number of patients continuing to maintain response up to 3 months.
Conclusion: We recommend the use of (methylprednisolone 20–30 mg/kg/d 3–5 days) followed by oral (prednisolone 2 mg/kg/d) due to rapid and sustained response
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Harun, Mirfat al-Sayyid& Afifi, Rasha Abd al-Rauf Abd al-Aziz& Habib, Nisrin Mustafa. 2018. Outcome of different treatment regimens used in newly diagnosed ITP pediatric patients. Egyptian Pediatric Association Gazette،Vol. 66, no. 2, pp.39-42.
https://search.emarefa.net/detail/BIM-836026
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Harun, Mirfat al-Sayyid…[et al.]. Outcome of different treatment regimens used in newly diagnosed ITP pediatric patients. Egyptian Pediatric Association Gazette Vol. 66, no. 2 (Jun. 2018), pp.39-42.
https://search.emarefa.net/detail/BIM-836026
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Harun, Mirfat al-Sayyid& Afifi, Rasha Abd al-Rauf Abd al-Aziz& Habib, Nisrin Mustafa. Outcome of different treatment regimens used in newly diagnosed ITP pediatric patients. Egyptian Pediatric Association Gazette. 2018. Vol. 66, no. 2, pp.39-42.
https://search.emarefa.net/detail/BIM-836026
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 42
رقم السجل
BIM-836026
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر