A case of toxic epidermal necrolysis successfully treated with low dose intravenous immunoglobulins and systemic corticosteroid
المؤلفون المشاركون
al-Kuthayri, Lutfi
Mercyamma, Varghese
al-Najjar, Tasnim
المصدر
العدد
المجلد 33، العدد 4 (31 يوليو/تموز 2018)، ص ص. 356-359، 4ص.
الناشر
المجلس العماني للاختصاصات الطبية
تاريخ النشر
2018-07-31
دولة النشر
سلطنة عمان
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Toxic epidermal necrolysis (TEN ), a severe form of Stevens-Johnson syndrome, is an acute life-threatening adverse drug reaction with a mortality rate of approximately 30%.
Primary treatment of TEN is usually supportive.
The use of intravenous immunoglobulin (IVIG) and corticosteroids are still uncertain, as there are only a limited number of studies comparing the usefulness of these treatments.
We report a case of a Filipino male patient who developed TEN , most likely due to one of the medications he received during his course of illness.
The patient was admitted to Sultan Qaboos Hospital, Salalah, with fever and diffuse painful maculopapular eruption, which became vesicular and bullous after few days, followed by shedding of large sheets of the epidermis.
The patient was admitted initially under medical care, and a diagnosis of TEN was considered later.
All unnecessary drugs were discontinued, and the patient was shifted to the burns unit.
In addition to standard supportive treatment, a combination therapy of systemic steroid and a low-dose IVIG (1.2 g/kg) divided over three days was administered.
This lowdose regimen of IVIG has a pharmacoeconomic benefit compared with the previous cumulative dose (3 g/kg), which is usually given by dermatologists in other institutions to patients with TEN .
The outcome was excellent, and the condition recovered almost completely two weeks after starting the treatment without sequelae
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Kuthayri, Lutfi& Mercyamma, Varghese& al-Najjar, Tasnim. 2018. A case of toxic epidermal necrolysis successfully treated with low dose intravenous immunoglobulins and systemic corticosteroid. Oman Medical Journal،Vol. 33, no. 4, pp.356-359.
https://search.emarefa.net/detail/BIM-838211
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Kuthayri, Lutfi…[et al.]. A case of toxic epidermal necrolysis successfully treated with low dose intravenous immunoglobulins and systemic corticosteroid. Oman Medical Journal Vol. 33, no. 4 (Jul. 2018), pp.356-359.
https://search.emarefa.net/detail/BIM-838211
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Kuthayri, Lutfi& Mercyamma, Varghese& al-Najjar, Tasnim. A case of toxic epidermal necrolysis successfully treated with low dose intravenous immunoglobulins and systemic corticosteroid. Oman Medical Journal. 2018. Vol. 33, no. 4, pp.356-359.
https://search.emarefa.net/detail/BIM-838211
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 359
رقم السجل
BIM-838211
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر