![](/images/graphics-bg.png)
First detection of FOX-1 AmpC β-lactamase gene expression among Escherichia coli isolated from abattoir samples in Abakaliki, Nigeria
المؤلفون المشاركون
Chika, Ejikeugwu
Charles, Esimone
Ifeanyichukwu, Iroha
Michael, Adikwu
المصدر
العدد
المجلد 33، العدد 3 (31 مايو/أيار 2018)، ص ص. 134-140، 7ص.
الناشر
المجلس العماني للاختصاصات الطبية
تاريخ النشر
2018-05-31
دولة النشر
سلطنة عمان
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objectives: Gram-negative bacteria represent the most relevant reservoir of resistance to antibiotics in the environment.
The natural selection of resistant clones of bacteria in the environment by antimicrobial selective pressure is a relevant mechanism for spreading antibiotic resistance traits in both the community and hospital environment.
This is common in scenarios where antimicrobials are used irrationally, and even in the propagation of livestock, poultry birds, and for other veterinary purposes.
This study sought to detect the prevalence of FOX-1 AmpC β-lactamase genes from abattoir samples.
Methods: The isolation of Escherichia coli, antimicrobial susceptibility testing, and β-lactamase characterization was carried out using standard microbiology techniques.
The production of AmpC β-lactamase was phenotypically carried out using the cefoxitin-cloxacillin double-disk synergy test (CC-DD ST), and FOX-1 AmpC genes was detected in the E.
coli isolates using multiplex polymerase chain reaction.
Results: Forty-eight E.
coli isolates were recovered from the anal swabs of cows and 35 (72.9%) isolates were positive for the production of β-lactamase.
Notably, high percentages of resistance to cefoxitin (91.7%), ceftriaxone (83.3%), imipenem (85.4%), ceftazidime (87.5%), ofloxacin (81.3%), and gentamicin (85.4%) were found.
FOX-1 genes were detected in three (6.3%) of the 48 E.
coli isolates phenotypically screened for AmpC enzyme production.
Conclusions: Abattoirs could represent a major reservoir of resistance genes especially AmpC β-lactamase, and this could serve as a route for the dissemination of multidrug-resistant bacteria in the community.
Thus, the molecular identification of drug-resistant genes is vital for a reliable epidemiological investigation and the forestalling of the emergence and spread of these organisms through the food chain in this region
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chika, Ejikeugwu& Charles, Esimone& Ifeanyichukwu, Iroha& Michael, Adikwu. 2018. First detection of FOX-1 AmpC β-lactamase gene expression among Escherichia coli isolated from abattoir samples in Abakaliki, Nigeria. Oman Medical Journal،Vol. 33, no. 3, pp.134-140.
https://search.emarefa.net/detail/BIM-838235
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chika, Ejikeugwu…[et al.]. First detection of FOX-1 AmpC β-lactamase gene expression among Escherichia coli isolated from abattoir samples in Abakaliki, Nigeria. Oman Medical Journal Vol. 33, no. 3 (May. 2018), pp.134-140.
https://search.emarefa.net/detail/BIM-838235
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chika, Ejikeugwu& Charles, Esimone& Ifeanyichukwu, Iroha& Michael, Adikwu. First detection of FOX-1 AmpC β-lactamase gene expression among Escherichia coli isolated from abattoir samples in Abakaliki, Nigeria. Oman Medical Journal. 2018. Vol. 33, no. 3, pp.134-140.
https://search.emarefa.net/detail/BIM-838235
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 139-140
رقم السجل
BIM-838235
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)