Effect of intensive exercise training and vitamin E supplementation on the content of rat brain neurotrophic factors
المؤلفون المشاركون
Fuad al-Din, Muhsin
Afzalpour, Muhammad Ismail
Chadorneshin, Husayn Tahiri
Abtahi Eivary, Sayyid Husayn
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 20، العدد 2 (28 فبراير/شباط 2018)، ص ص. 1-9، 9ص.
الناشر
تاريخ النشر
2018-02-28
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background: Hydrogen Peroxide (H2O2) and Tumor Necrosis Factor alpha (TNF-α) increase Brain-Derived Neurotrophic Factor (BDNF) and Glial Cell Line-Derived Neurotrophic Factor (GDNF) expression.
Athletics use anti-oxidant and anti-inflammatory supplementations to reduce H2O2 and TNF-α level.
There is insufficient information about vitamin E supplementation on neurotrophic adaptations induced by intensive exercise training.
Objectives: The aim of the present study was to investigate the effects of intensive exercise training in combination with vitamin E supplementation on BDNF and GDNF content of rat brain.
Methods: In an experimental study in Iran, 40 male Wistar rats were randomly assigned to Control (C), Sham (S), Vitamin E (V.TE), Exercise training (ET), Exercise training + Vitamin E (ET+V.TE) groups, with 8 rats in each group.
Exercise training on treadmill (27 m/minute) was carried out in combination with vitamin E supplementation (60 mg/kg/day) for six weeks.
Statistical significance was determined at P < 0.05 using one-way analysis of variance (SPSS software, version 16.0).
Results: Vitamin E supplementation increased brain vitamin E levels in V.TE and ET+V.TE groups (P = 0.001).
Significant increments in the levels of H2O2 (P = 0.007), TNF-α, (P = 0.001), BDNF (P = 0.001), and GDNF (P = 0.001) in the ET group were shown; however, vitamin E supplementation could not change exercise-induced increases on the above-mentioned factors in the ET+V.TE group (the p-values were equal to 0.024, 0.001, 0.001, and 0.001 respectively).
Conclusion: Intensive exercise training increases BDNF and GDNF contents in the whole brain of rats, yet vitamin E does not influence neurotrophic adaptations induced by intensive exercise training.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fuad al-Din, Muhsin& Afzalpour, Muhammad Ismail& Chadorneshin, Husayn Tahiri& Abtahi Eivary, Sayyid Husayn. 2018. Effect of intensive exercise training and vitamin E supplementation on the content of rat brain neurotrophic factors. Iranian Red Crescent Medical Journal،Vol. 20, no. 2, pp.1-9.
https://search.emarefa.net/detail/BIM-840411
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fuad al-Din, Muhsin…[et al.]. Effect of intensive exercise training and vitamin E supplementation on the content of rat brain neurotrophic factors. Iranian Red Crescent Medical Journal Vol. 20, no. 2 (Feb. 2018), pp.1-9.
https://search.emarefa.net/detail/BIM-840411
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fuad al-Din, Muhsin& Afzalpour, Muhammad Ismail& Chadorneshin, Husayn Tahiri& Abtahi Eivary, Sayyid Husayn. Effect of intensive exercise training and vitamin E supplementation on the content of rat brain neurotrophic factors. Iranian Red Crescent Medical Journal. 2018. Vol. 20, no. 2, pp.1-9.
https://search.emarefa.net/detail/BIM-840411
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 8-9
رقم السجل
BIM-840411
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر