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Effect of intensive exercise training and vitamin E supplementation on the content of rat brain neurotrophic factors
المؤلفون المشاركون
Fuad al-Din, Muhsin
Afzalpour, Muhammad Ismail
Chadorneshin, Husayn Tahiri
Abtahi Eivary, Sayyid Husayn
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 20، العدد 2 (28 فبراير/شباط 2018)، ص ص. 1-9، 9ص.
الناشر
تاريخ النشر
2018-02-28
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background: Hydrogen Peroxide (H2O2) and Tumor Necrosis Factor alpha (TNF-α) increase Brain-Derived Neurotrophic Factor (BDNF) and Glial Cell Line-Derived Neurotrophic Factor (GDNF) expression.
Athletics use anti-oxidant and anti-inflammatory supplementations to reduce H2O2 and TNF-α level.
There is insufficient information about vitamin E supplementation on neurotrophic adaptations induced by intensive exercise training.
Objectives: The aim of the present study was to investigate the effects of intensive exercise training in combination with vitamin E supplementation on BDNF and GDNF content of rat brain.
Methods: In an experimental study in Iran, 40 male Wistar rats were randomly assigned to Control (C), Sham (S), Vitamin E (V.TE), Exercise training (ET), Exercise training + Vitamin E (ET+V.TE) groups, with 8 rats in each group.
Exercise training on treadmill (27 m/minute) was carried out in combination with vitamin E supplementation (60 mg/kg/day) for six weeks.
Statistical significance was determined at P < 0.05 using one-way analysis of variance (SPSS software, version 16.0).
Results: Vitamin E supplementation increased brain vitamin E levels in V.TE and ET+V.TE groups (P = 0.001).
Significant increments in the levels of H2O2 (P = 0.007), TNF-α, (P = 0.001), BDNF (P = 0.001), and GDNF (P = 0.001) in the ET group were shown; however, vitamin E supplementation could not change exercise-induced increases on the above-mentioned factors in the ET+V.TE group (the p-values were equal to 0.024, 0.001, 0.001, and 0.001 respectively).
Conclusion: Intensive exercise training increases BDNF and GDNF contents in the whole brain of rats, yet vitamin E does not influence neurotrophic adaptations induced by intensive exercise training.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fuad al-Din, Muhsin& Afzalpour, Muhammad Ismail& Chadorneshin, Husayn Tahiri& Abtahi Eivary, Sayyid Husayn. 2018. Effect of intensive exercise training and vitamin E supplementation on the content of rat brain neurotrophic factors. Iranian Red Crescent Medical Journal،Vol. 20, no. 2, pp.1-9.
https://search.emarefa.net/detail/BIM-840411
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fuad al-Din, Muhsin…[et al.]. Effect of intensive exercise training and vitamin E supplementation on the content of rat brain neurotrophic factors. Iranian Red Crescent Medical Journal Vol. 20, no. 2 (Feb. 2018), pp.1-9.
https://search.emarefa.net/detail/BIM-840411
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fuad al-Din, Muhsin& Afzalpour, Muhammad Ismail& Chadorneshin, Husayn Tahiri& Abtahi Eivary, Sayyid Husayn. Effect of intensive exercise training and vitamin E supplementation on the content of rat brain neurotrophic factors. Iranian Red Crescent Medical Journal. 2018. Vol. 20, no. 2, pp.1-9.
https://search.emarefa.net/detail/BIM-840411
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 8-9
رقم السجل
BIM-840411
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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