تواتر الزمر الدموية ABO و باقي النظم الدموية في سورية

الملخص EN

Background& Objective: Blood groups are of greatclinical importancein blood transfusion and in tissue transplantation.

In fact,the discovery ofthe ABOsystemwas oneof the most importantfactors in making the practice ofblood transfusion possible.The person`sABO bloodtypeis usedin paternity suits,in forensic science andin thestudy ofdifferent populations.

To provide accurate anddocumented information about the frequency ofABO and Rh Dblood groups in oursocietyand to identifythe frequency of the most important otherblood systems :Rh, K, Duffy, Kidd.

Materials & Methods: A retrospective Analytical study ofthe results ofABO, Rh Dblood grouping and followingblood systems: Rh, K, Duffy and Kiddfor blood donors atthe Damascus University Blood Transfusion Center during the period2004 -2008,using themicroplate and gelfiltration techniques.

Results: The number of persons admitted to blood donation during the study period was 74,504 people, their ABO blood groups were distributed as follows: A: 39.2%, B: 18.6%, O: 34.6% and AB: 7.6%.

As for the Rh D phenotype, was positive in 90% while negative in 10%.

The frequency of Rh, K phenotype was as follows: C: 73.8%, E: 24.6%, c: 73.9%, e: 97.4%, while K was 8.1%.

As for the phenotype of Duffy,Kidd systems were: Fya 65%, Fyb 67%, while Jka 79% and Jkb70%.

Conclusion: Our study results show that the trend of the frequency of blood groupsin our country is: A> O> B> AB and Rh D is negative in 10% while positive in 90%.

The knowledge of the frequency of antigens of other blood systems Rh, K, Duffy, Kidd in blood donors help blood transfusion centers toprovidecompatible units for patients with repeated blood transfusion as patients with thalassemia and sickle cell anemia, also provides a very important database for donors with known Phenotype