Biological activity of levan produced from Rhizospheric soil bacterium Brachybacterium phenoliresistens KX139300

الملخص EN

Levan is an exopolysaccharide produced by various microorganisms and has a variety of applications.

In this research, the aim was to demonstrate the biological activity of levan which produced from B.

phenoliresistens KX139300.

These were done via study the antioxidant, anti-inflammatory, anticancer and antileishmanial activities in vitro.

The antioxidant levan was shown 80.9% activity at 1250 µg/mL concentration.

The efficient anti-inflammatory activity of 88% protein inhibition was noticed with levan concentration at 35 µg/mL.

The cytotoxic activity of levan at 2500 µg/mL concentration showed a maximum cytotoxic effect on L20B cell line and promastigotes of Leishmani tropica.

Levan has dose-dependent anticancer and antileishmanial activities.

An addition to the antioxidant, anti-inflammatory and anticancer potential activities of levan, it can be concluded that levan produced from B.

phenoliresistens can efficiently be applied as an antileishmanial agent