Effects of PM2.5 and NO2 on the 8-isoprostane and lung function indices of FVC and FEV1 in students of Ahvaz city, Iran

الملخص EN

The aim of this study was to determine the correlation between PM2.5 and NO2 pollutants and oxidative stress marker (8-isoprostane) and lung function tests (FVC and FEV1) in healthy children who were living and studying in three different areas of Ahvaz city including A1: Naderi site with high traffic, A2: Alavi Alley site with average traffic, and A3: Ein 2 site with low traffic (a rural area on the suburb of Ahvaz).

30 students in the 12–13 year-old range were selected from each studied zone (1, 2 and 3 sites) during three months of year.

Of each student, one sample was taken every two weeks to measure 8-isoprostane of exhaled breath condensate (EBC).

Air pollution data were collected from three air quality monitoring stations.

Also, the relationship between air pollution and 8-isoprostane as well as lung function tests were determined using generalized estimating equations (GEE).

The mean concentration of PM2.5 and NO2 in A1,