Hormone replacement therapy and postmenopausal cardiovascular events : a meta-analysis
المؤلفون المشاركون
Salaminia, Shirvan
Muhsin Zadah, Yusuf
Muti al-Din, Murtada
Dousti, Majid
Sayehmiri, Fatimah
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 21، العدد 2 (28 فبراير/شباط 2019)، ص ص. 1-13، 13ص.
الناشر
تاريخ النشر
2019-02-28
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
13
التخصصات الرئيسية
الموضوعات
الملخص EN
Context: Hormonereplacement therapy (HRT) is widely used to control postmenopausal symptoms.
This therapy is also used to prevent diseases such as osteoporosis and dementia.
However, clinical trials suggest some negative effects regarding postmenopausal HRT.
This study evaluates the effects of HRT on postmenopausal cardiovascular events.
Evidence Acquisition: We collected data from 32 articles by using valid keywords and searching databases of PubMed, Medlib, ScienceDirect, EmBase, Scopus, Index Copernicus, SID, and Iranmedex.
Analysis was performed by comparing three groups of postmenopausal women: combined hormone therapy (estrogen + progesterone), estrogen alone treated group, and placebo-receiving group (control group).
Data were analyzed using the random effect model meta-analysis by using R software and Stata software Version 11.2.
Results: Of the collected 32 studies between 1998 and 2016, there were 1277686 subjects with an average age of 60.6 years.
The prevalence of myocardial infarction were (2.64%), coronary heart disease (1.7%), stroke (254%), cardiovascular death (1.54%), revascularization(3.26 %), and cerebrovascular disease (CVD) (2.78%) in the combined hormone therapy group.
Also, in the estrogen-treated group were 2.95%, 3.41%, 2.49%, 2.8%, - , 3.14%, respectively.
In the placebo-receiving group these events were 2.09%, 2.73%, 2.9%, 2.25%, 4.96%, and 11.92, respectively.
The results showed that estrogen therapy could increase the incidence of stroke.
Moreover, HRT could have positive effects on the serum lipid profile in postmenopausal women.
Conclusion: Postmenopausal HRT appears to be non-effective on coronary artery disease, revascularization, myocardial infarction, and cardiac-related deaths; however, it could play a role in increasing the stroke rate.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Salaminia, Shirvan& Muhsin Zadah, Yusuf& Muti al-Din, Murtada& Sayehmiri, Fatimah& Dousti, Majid. 2019. Hormone replacement therapy and postmenopausal cardiovascular events : a meta-analysis. Iranian Red Crescent Medical Journal،Vol. 21, no. 2, pp.1-13.
https://search.emarefa.net/detail/BIM-888700
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Salaminia, Shirvan…[et al.]. Hormone replacement therapy and postmenopausal cardiovascular events : a meta-analysis. Iranian Red Crescent Medical Journal Vol. 21, no. 2 (Feb. 2019), pp.1-13.
https://search.emarefa.net/detail/BIM-888700
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Salaminia, Shirvan& Muhsin Zadah, Yusuf& Muti al-Din, Murtada& Sayehmiri, Fatimah& Dousti, Majid. Hormone replacement therapy and postmenopausal cardiovascular events : a meta-analysis. Iranian Red Crescent Medical Journal. 2019. Vol. 21, no. 2, pp.1-13.
https://search.emarefa.net/detail/BIM-888700
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes appendices : p. 12-13
رقم السجل
BIM-888700
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر