Effects of compound lobelia oral liquid on acute pharyngitis rabbits model

المؤلفون المشاركون

Miao, Mingsan
Liu, Baosong
Peng, Mengfan
Bai, Ming

المصدر

Saudi Journal of Biological Sciences

العدد

المجلد 26، العدد 4 (31 مايو/أيار 2019)، ص ص. 816-820، 5ص.

الناشر

الجمعية السعودية لعلوم الحياة

تاريخ النشر

2019-05-31

دولة النشر

السعودية

عدد الصفحات

5

التخصصات الرئيسية

الأحياء

الموضوعات

الملخص EN

Aims : Explore the effect of compound lobelia oral liquid on acute pharyngitis rabbits model caused by ammonium hydroxide, evaluate its curative effect.

Methods : Acute pharyngitis rabbit model was prepared by ammonia spray at pharyngeal.

After 1 h of the last administration, score the pharyngeal tissue symptoms of rabbits under the condition of naked eyes (score according to the score criteria).

Then, take blood from the marginal auricular vein for routine blood tests and serum TNF-a level measure.

Take pharyngeal tissue for HE staining, and observe its pathological changes under the microscope.

Results : Compared with the blank group, the pharyngeal tissue symptom score and serum TNF-a level in the model group were significantly increased (P < 0.01).

The results of blood routine showed that the number of white blood cells and lymphocytes in the model group increased significantly (P < 0.01), and neutrophilic granulocyte percentage decreased significantly (P < 0.01).

The infiltration of inflammatory cells in the pharynx tissue was obvious and pathological changes were observed.

Compared with the model group, large, middle and small doses of compound lobelia oral liquid group could reduce the scores of pharyngeal tissue symptoms in rabbits with acute pharyngitis induced by ammonia.

The large and middle dose compound lobelia oral liquid group could significantly reduce serum TNF-a level and neutrophilic granulocyte percentage, significantly increase the number of white blood cells and lymphocytes (P < 0.01) ; The small dose compound lobelia oral liquid group could significantly reduce the number of white blood cells and lymphocytes (P < 0.01), there was an increasing tendency to neutrophils and a decreasing tendency to serum TNF-a, but no statistical significance.

The large, middle and small doses of compound lobelia oral liquid group all could improve the pathological changes of pharyngeal tissue inflammatory infiltration.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Miao, Mingsan& Peng, Mengfan& Liu, Baosong& Bai, Ming. 2019. Effects of compound lobelia oral liquid on acute pharyngitis rabbits model. Saudi Journal of Biological Sciences،Vol. 26, no. 4, pp.816-820.
https://search.emarefa.net/detail/BIM-891159

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Miao, Mingsan…[et al.]. Effects of compound lobelia oral liquid on acute pharyngitis rabbits model. Saudi Journal of Biological Sciences Vol. 26, no. 4 (May. 2019), pp.816-820.
https://search.emarefa.net/detail/BIM-891159

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Miao, Mingsan& Peng, Mengfan& Liu, Baosong& Bai, Ming. Effects of compound lobelia oral liquid on acute pharyngitis rabbits model. Saudi Journal of Biological Sciences. 2019. Vol. 26, no. 4, pp.816-820.
https://search.emarefa.net/detail/BIM-891159

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references : p. 819-820

رقم السجل

BIM-891159