A rhinofacial conidiobolus coronatus fungal infection presenting as an intranasal tumour

الملخص EN

Conidiobolomycosis is a rare fungal infection that affects adults in tropical regions.

We report a 42-year-old male patient who was referred to the Sulaiman Al Habib Hospital, Dubai, United Arab Emirates (UAE), in 2013 with excessive nasal bleeding and a suspected nasal tumour.

He reported having briefly visited central India nine months previously.

Computed tomography and magnetic resonance imaging showed a highly vascularised mass in the nasal cavity.

However, after surgical excision, initial treatment with amphotericin B deoxycholate was unsuccessful and the disease progressed, leading to external and internal nasal deformation and necessitating further excision and facial reconstruction.

Histopathological analysis of the second biopsy revealed Splendore- Hoeppli changes consistent with a fungal infection.

Microbiological findings subsequently confirmed Conidiobolus coronatus.

Subsequently, the patient was successfully treated with a combination of itraconazole and fluconazole.

To the best of the authors’ knowledge, this is the first report of a case of rhinofacial conidiobolomycosis from the UAE.