Estimation of the most appropriate threshold for lesion delineation and volumetric quantification in 18F-FDG PET
المؤلفون المشاركون
Khalil, Majdi M.
al-Ramlawi, Shaban
Shafaa, Midhat W.
Abd al-Jawad H.
المصدر
Arab Journal of Nuclear Sciences and Applications
العدد
المجلد 52، العدد 2 (30 إبريل/نيسان 2019)، ص ص. 169-180، 12ص.
الناشر
الجمعية المصرية للعلوم النووية و تطبيقاتها
تاريخ النشر
2019-04-30
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الموضوعات
الملخص EN
The function formulation to estimate the most appropriate percentage value of maximum Standardized uptake value as a threshold for automatic lesion delineation in PET/CT exam considering lesion to background ratio and the lesion volume determined by computed tomography "CT" tissue segmentation software was investigated.
The phantom consists of two parts: a hollow cylinder of a diameter (18.6 cm), length (21.6 cm), and multiple spheres.
The sphere assembly contains 4 spheres of different volumes.
The phantom was filled with water containing 18F-Fluorodeoxyglucose (18F-FDG) forming the sphere versus background activity concentration (μCi/ml) ratios 3:1, 5:1, 8:1, 10:1, 12:1, 14:1 and15:1.
For each scan, the sphere set is aligned in the center of the field of view "FOV" and the time per bed position is similar to that of the routine work 3min.
Graphs were plotted of standardized uptake value threshold versus lesion-size at different sphere/background ratio using MS Excel.
There was a logarithmic decrease in threshold with an increase in lesion size.
The most appropriate SUV threshold for each lesion at different lesion/background was estimated from the plotted graphs.
Four tests namely, (5:1, 8:1, 12:1 and 15:1) were used to generate a 3D general function to estimate threshold using the contrast ratio and lesion volume as inputs and the other three tests (3:1, 10:1 and 14:1) were used for the function validation.
The Normalized mean square error (NMSE) is used to measure the convergence between estimated and measured data set.
The created logarithmic functions offer an easy and simple way to estimate the percentage value of SUV max as a threshold using the lesion/background ratio and sphere volume(or Diameter) from CT images as inputs to be used for lesion delineation and volume determination in PET images that were verified and the NMSE=6.2.
It could be concluded that the created formula is useful and easy to estimate the most appropriate SUV threshold for automatically definite lesion volume.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Ramlawi, Shaban& Abd al-Jawad H.& Khalil, Majdi M.& Shafaa, Midhat W.. 2019. Estimation of the most appropriate threshold for lesion delineation and volumetric quantification in 18F-FDG PET. Arab Journal of Nuclear Sciences and Applications،Vol. 52, no. 2, pp.169-180.
https://search.emarefa.net/detail/BIM-892520
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Ramlawi, Shaban…[et al.]. Estimation of the most appropriate threshold for lesion delineation and volumetric quantification in 18F-FDG PET. Arab Journal of Nuclear Sciences and Applications Vol. 52, no. 2 (Apr. 2019), pp.169-180.
https://search.emarefa.net/detail/BIM-892520
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Ramlawi, Shaban& Abd al-Jawad H.& Khalil, Majdi M.& Shafaa, Midhat W.. Estimation of the most appropriate threshold for lesion delineation and volumetric quantification in 18F-FDG PET. Arab Journal of Nuclear Sciences and Applications. 2019. Vol. 52, no. 2, pp.169-180.
https://search.emarefa.net/detail/BIM-892520
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 179-180
رقم السجل
BIM-892520
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر