Assessment of stromal eosinophilia in cutaneous squamous cell carcinoma
المؤلفون المشاركون
Muhammad, Haydar Latif
Abu Daqqah, Farah Falah Hasan
Yahya, Ala Qasim
Fadl, Muhammad Haydar
المصدر
al-Kindy College Medical Journal
العدد
المجلد 15، العدد 1 (30 يونيو/حزيران 2019)، ص ص. 30-35، 6ص.
الناشر
تاريخ النشر
2019-06-30
دولة النشر
العراق
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Background: Tumor associated tissue eosinophilia (TATE) has been described in a variety of neoplasms.
In regard to squamous cell carcinoma, some studies worldwide done to assess stromal eosinophilia in oral and cervical squamous cell carcinoma.
The objectives of this study is to evaluate the association of stromal eosinophilic infiltration of cutaneous squamous cell carcinoma and to detect the significance of this association.
Aim of the study The aim of our study is to establish the relationship between the degree of stromal eosinophilia and the level of invasion and the histological grade in cutaneous squamous cell carcinoma.
Methods: In this retrospective study done at the histopathology department of al Wasity teaching hospital for orthopedic and plastic surgery in Baghdad, all paraffin embedded blocks for excisional biopsies diagnosed as primary cutaneous squamous cell carcinoma from December 2015 to January 2017 were retrieved.
Incisional biopsies and those with margin positive tumor cells were excluded.
After a careful evaluation for histological grading and assessment of level of invasion according to an established histological criteria , the assessment of tissue eosinophils was done by three pathologist through counting eosinophils in tumor stroma in 10 high power field using a light microscope and categorized as none (0,),low (1-4),medium (5-19)and high (more than 20).
Results : of 56 cases of primary cutaneous squamous cell carcinoma 48(85.7%) cases were conventional .The mean age was 43.14 ± 1.76 .Regarding conventional squamous cell carcinoma ,of 48 cases 30(62.5) were well differentiated,16(33.3%) had clarck level III,18(37.5%) had clarck level IV and 14(29.1%) had Clark level V .There is a significant statistical relationship between histological grading of tissue eosinophilia and level of invasion with p value 0.044 and a non-significant relationship with degree of differentiation.
Conclusion :The majority of cutaneous squamous cell carcinomas were conventional well differentiated with a mean age in the fifth decade of life ,a male predominance and often had a degree of stromal eosinophilia that is strongly associated with the level of invasion .Thus more Intense tissue eosinophilia is correlated with a higher level of stromal invasion.
The significance of such an association should be regarded as either a potential predictive tool for stromal invasion in small incisional biopsy or as a prognostic indicator that could be included in the pathology report for conventional squamous cell carcinoma
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abu Daqqah, Farah Falah Hasan& Yahya, Ala Qasim& Fadl, Muhammad Haydar& Muhammad, Haydar Latif. 2019. Assessment of stromal eosinophilia in cutaneous squamous cell carcinoma. al-Kindy College Medical Journal،Vol. 15, no. 1, pp.30-35.
https://search.emarefa.net/detail/BIM-893575
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abu Daqqah, Farah Falah Hasan…[et al.]. Assessment of stromal eosinophilia in cutaneous squamous cell carcinoma. al-Kindy College Medical Journal Vol. 15, no. 1 (2019), pp.30-35.
https://search.emarefa.net/detail/BIM-893575
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abu Daqqah, Farah Falah Hasan& Yahya, Ala Qasim& Fadl, Muhammad Haydar& Muhammad, Haydar Latif. Assessment of stromal eosinophilia in cutaneous squamous cell carcinoma. al-Kindy College Medical Journal. 2019. Vol. 15, no. 1, pp.30-35.
https://search.emarefa.net/detail/BIM-893575
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 34-35
رقم السجل
BIM-893575
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر