Effect of betaine on hepatic and renal functions in acrylamide treated rats
العناوين الأخرى
تأثير البيتين (betaine) على وظائف الكبد و الكلية في الجرذان المعاملة بالأكريلامايد : المبحث الثاني
المؤلفون المشاركون
Ramadan, Sadiq Jafar
Khudayr, Khalisah Kazim
المصدر
Iraqi Journal of Veterinary Medicine
العدد
المجلد 43، العدد 1 (30 يونيو/حزيران 2019)، ص ص. 138-147، 10ص.
الناشر
تاريخ النشر
2019-06-30
دولة النشر
العراق
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
This study was designed to evaluate the ameliorative role of betaine on hepatic and renal dysfunction caused by acrylamide in female rats.
Thirty two (32) adult female rats were randomly and equally divided into four groups (G1, G2, G3 and G4) and were treated for (65) days as following: Group G1 (Control group), G2: rats were intubated 250mg/kg B.W of betaine; animals in group G3 were intubated 1mg/kg B.W of acrylamide, in addition to acrylamide.
250mg/kg B.W of betaine were administered orally to rats in groups G4.
Fasting (8-12 hrs.) blood samples were collected by cardio puncture technique at the end of the experiment, serum were collected for measuring the following parameters A: liver enzyme makers; serum activity of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP) B; renal function parameters including: serum creatinine, urea and uric acid concentration.
The hepato and renal protective effect of betaine was clarified in groups (G2 and G4) manifested by significant decrease in serum, ALT, AST and ALP activity, as well as significant decrease in serum creatinine, urea and uric acid concentration comparing to acrylamide (G3) treated group.
Such functional changes were accompanied with structural (histopathological) alteration in hepatic and renal tissue.
In conclusion, the results of the current study documented the negative effect of acrylamide on liver and kidney function and documented hepatorenal protective effect of betaine.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ramadan, Sadiq Jafar& Khudayr, Khalisah Kazim. 2019. Effect of betaine on hepatic and renal functions in acrylamide treated rats. Iraqi Journal of Veterinary Medicine،Vol. 43, no. 1, pp.138-147.
https://search.emarefa.net/detail/BIM-894258
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ramadan, Sadiq Jafar& Khudayr, Khalisah Kazim. Effect of betaine on hepatic and renal functions in acrylamide treated rats. Iraqi Journal of Veterinary Medicine Vol. 43, no. 1 (2019), pp.138-147.
https://search.emarefa.net/detail/BIM-894258
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ramadan, Sadiq Jafar& Khudayr, Khalisah Kazim. Effect of betaine on hepatic and renal functions in acrylamide treated rats. Iraqi Journal of Veterinary Medicine. 2019. Vol. 43, no. 1, pp.138-147.
https://search.emarefa.net/detail/BIM-894258
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 143-147
رقم السجل
BIM-894258
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر