LCZ696 effect on improving quality of life and ejection fraction of palestinian patients with heart failure and reduced ejection fraction

المؤلفون المشاركون

Aql, Raid
Salih, Muhannad
Jubbah, Wafa

المصدر

Journal of the Royal Medical Services

العدد

المجلد 26، العدد 2 (31 أغسطس/آب 2019)، ص ص. 73-78، 6ص.

الناشر

الخدمات الطبية الملكية الأردنية

تاريخ النشر

2019-08-31

دولة النشر

الأردن

عدد الصفحات

6

التخصصات الرئيسية

الطب البشري

الموضوعات

الملخص EN

Objective: With the LCZ696 (sacubutril/valsartan) being a new add-on treatment to patients with congestive heart failure and reduced ejection fraction, this study aims to show the effects of LCZ696 on ejection fraction (first reported) and the quality of life of the Palestinian population with heart failure.

Methods: The first 102 patients who were started on this medication were examined.

In addition, all demographic data were tabulated, and all follow-up visits were analyzed.

The quality of life based on the New York Heart Association (NYHA) classification was recorded.

All hospital admissions, deaths, labs, and echocardiograms were recorded.

The length of study was 6–12 months (mean of nine months), and all patients, signed an informed consent form allowing for their charts to be reviewed.

Results: The LCZ696 has been studied for over a period of 6–12 months on 102 patients with heart failure and reduced ejection fraction.

Measurement of ejection fraction was measured by standard protocol before, during, and after initiating LCZ696.

Records showed a significant improvement in the left ventricular EF and in their NYHA classification of heart failure.

Conclusion: Despite its limitations, we think that LCZ696 (sacubutril/valsartan) has a very promising outcome on the quality of life and the ejection fraction of a group of patients with congestive heart failure and reduced ejection fraction.

There were statistical improvements on the quality of life as well as in the ejection fraction (first reported) with an acceptable safety margin.

However, such effect needs to be replicated in other prospective and retrospective studies

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Aql, Raid& Salih, Muhannad& Jubbah, Wafa. 2019. LCZ696 effect on improving quality of life and ejection fraction of palestinian patients with heart failure and reduced ejection fraction. Journal of the Royal Medical Services،Vol. 26, no. 2, pp.73-78.
https://search.emarefa.net/detail/BIM-894365

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Aql, Raid…[et al.]. LCZ696 effect on improving quality of life and ejection fraction of palestinian patients with heart failure and reduced ejection fraction. Journal of the Royal Medical Services Vol. 26, no. 2 (Aug. 2019), pp.73-78.
https://search.emarefa.net/detail/BIM-894365

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Aql, Raid& Salih, Muhannad& Jubbah, Wafa. LCZ696 effect on improving quality of life and ejection fraction of palestinian patients with heart failure and reduced ejection fraction. Journal of the Royal Medical Services. 2019. Vol. 26, no. 2, pp.73-78.
https://search.emarefa.net/detail/BIM-894365

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references : p. 77-78

رقم السجل

BIM-894365