A cerebellar high-grade neuroepithelial tumour with bcor alteration in a five-year-old child : a case report

الملخص EN

New groups of high-grade neuroepithelial tumours (HGNET) have emerged from the reclassification of central nervous system (CNS) embryonal tumours that have recognised CNS HGNET with BCOR alteration (CNS HGNET-BCOR).

We report a two-year, nine-month-old Omani boy who presented to the Royal Hospital, Muscat, Oman, in 2015 with subacute head tilting and neck pain.

A well-defined cerebellar lesion was found and he was treated with standard chemoradiotherapy.

After a relapse at the age of five years, molecular testing revealed a BCOR alteration.

He was treated with further surgery and high-dose chemotherapy; unfortunately, he relapsed and died three years after he was diagnosed