Effect of alpha lipoic acid on some reproductive hormones in adult male wister rats exposed to hydrogen peroxide

العناوين الأخرى

دور حمض الفا الليبويك على صورة هورمونات التكاثر في ذكور جرذان الوستر البالغة المعاملة ببيروكسيد الهيدروجين

المؤلفون المشاركون

al-Uqayli, Bara Najm Abd Allah
Hayawi, Muhammad Salih Ulwan

المصدر

Kufa Journal for Veterinary Medical Sciences

العدد

المجلد 10، العدد 1 (30 يونيو/حزيران 2019)، ص ص. 79-87، 9ص.

الناشر

جامعة الكوفة كلية الطب البيطري

تاريخ النشر

2019-06-30

دولة النشر

العراق

عدد الصفحات

9

التخصصات الرئيسية

الطب البيطري

الملخص EN

The present study was aimed to investigate the role of alpha lipoic acid (ALA) on reproductive hormonal profile in adult male Wister rats treated with hydrogen Peroxide.

Forty adult male rats were divided randomly into four equal groups (10 rats /group) and were handled daily as follows for 56 days: Control group (C) were intubated distilled water and received tap water ; group T1 were intubated 60mg/kg B.W of ALA and received tap water; group T2 administered hydrogen peroxide H2O2 in tap water at concentration of 0.05%, while group T3 were intubated 60mg/kg B.W of ALA and received ordinary tap water containing 0.05% H2O2.

Blood samples were collected at 0, 28 and 56 days of the experimental periods for measurement of serum follicular stimulation hormone (FSH), lutelizing hormone (LH) and testosterone (T) concentrations.

The results revealed that group T2 showed a significant decrease in FSH and testosterone concentrations.

While there were significant increase in previous parameters in T3 group compared to T2 group.

Whereas, rats in group T3 shows significant improvement in above serum hormonal profile by repairing role of alpha lipoic acid against hydrogen peroxide in (group T2).

In conclusion, alpha lipoic acid mitigated the deleterious effect of that-induced H2O2 induced pituitary-testicular dysfunction through antioxidant mechanism by free radical scavenging properties

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Hayawi, Muhammad Salih Ulwan& al-Uqayli, Bara Najm Abd Allah. 2019. Effect of alpha lipoic acid on some reproductive hormones in adult male wister rats exposed to hydrogen peroxide. Kufa Journal for Veterinary Medical Sciences،Vol. 10, no. 1, pp.79-87.
https://search.emarefa.net/detail/BIM-895938

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Hayawi, Muhammad Salih Ulwan& al-Uqayli, Bara Najm Abd Allah. Effect of alpha lipoic acid on some reproductive hormones in adult male wister rats exposed to hydrogen peroxide. Kufa Journal for Veterinary Medical Sciences Vol. 10, no. 1 (2019), pp.79-87.
https://search.emarefa.net/detail/BIM-895938

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Hayawi, Muhammad Salih Ulwan& al-Uqayli, Bara Najm Abd Allah. Effect of alpha lipoic acid on some reproductive hormones in adult male wister rats exposed to hydrogen peroxide. Kufa Journal for Veterinary Medical Sciences. 2019. Vol. 10, no. 1, pp.79-87.
https://search.emarefa.net/detail/BIM-895938

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references : p. 86-87

رقم السجل

BIM-895938