A single-center 4-year experience with 47 pediatric renal transplants : evolving trends
المؤلفون المشاركون
Habhab, Wail T.
al-Hinnawi, Hani M.
Fahmi, Ahmad E.
al-Harbi, Nafa
al-Hashimi, Ahmad
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 29، العدد 6 (31 ديسمبر/كانون الأول 2018)، ص ص. 1303-1310، 8ص.
الناشر
تاريخ النشر
2018-12-31
دولة النشر
السعودية
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Outcome of pediatric kidney transplantation (KT) has improved over the last several decades.
We retrospectively reviewed the outcomes pediatric KT in King Faisal Specialist Hospital and Research Center-Jeddah, Saudi Arabia.
Between May 2013 and November 2016, we performed renal transplantation in 47 children, 30 (64%) males, and 17 (36%) females.
All patients received antibody induction with basiliximab or antithymocyte globulin along with triple immunosuppressive therapy with tacrolimus, mycophenolate mofetil and steroids.
Twenty-four (51%) and 14 (30%) patients were on hemodialysis and peritoneal dialysis, respectively.
Average duration on dialysis was 18.3 months.
Nine patients (19%) had preemptive transplant.
Forty-five patients (95.7%) received kidneys from living donors, 38 (83%) males and nine (17%) females, mean age (years), and body mass index were 30.8 ± 8.82 and 23.8 ± 4.54, respectively.
Forty-one donors had left nephrectomy.
Four right nephrectomies were reported, all of them were through open nephrectomy.
Open nephrectomy was reported in 21 (46%) patients.
Several laparoscopic nephrectomy techniques were performed; conventional laparoscopic donor nephrectomy, laparo-endoscopic single-site donor nephrectomy, and hand-assisted laparoscopic surgery in 10, 11, and three patients, respectively.
The most common etiologies of end-stage renal disease were focal segmental glomerulosclerosis 19%, posterior urethral valve 8.5%, and congenital abnormalities 8.5% respectively.
With a mean follow-up of 54 months, one and 4-year graft survival rates were 95.7% and 91.5%, respectively.
One-and four-year patient survival rates were 100%.
Outcomes were similar in patients < or ≥10 years.
The graft survival was comparable in laparoscopic versus open donor nephrectomy (P = 0.72).
Average serum creatinine was 0.85, 0.79, 0.79, and 0.84 at 7, 30, 90, 365 days, respectively.
Four patients lost their graft due to renal vein thrombosis, chronic allograft nephropathy (cadaveric donor), Antibody-mediated rejection, and hemolytic-uremic syndrome at 0.75, 9, 19, and 24 months, respectively.
The incidences of acute rejection and major infection were 2% and 4%, respectively.
One patient developed posttransplant lympho-proliferative disease that was treated and is still with excellent graft function.
Our pediatric KT experience is encouraging.
Acute rejection, patient, and graft survival rates are similar and even better than many of western reports.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Hinnawi, Hani M.& al-Hashimi, Ahmad& al-Harbi, Nafa& Habhab, Wail T.& Fahmi, Ahmad E.. 2018. A single-center 4-year experience with 47 pediatric renal transplants : evolving trends. Saudi Journal of Kidney Diseases and Transplantation،Vol. 29, no. 6, pp.1303-1310.
https://search.emarefa.net/detail/BIM-896379
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Hinnawi, Hani M.…[et al.]. A single-center 4-year experience with 47 pediatric renal transplants : evolving trends. Saudi Journal of Kidney Diseases and Transplantation Vol. 29, no. 6 (Nov. / Dec. 2018), pp.1303-1310.
https://search.emarefa.net/detail/BIM-896379
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Hinnawi, Hani M.& al-Hashimi, Ahmad& al-Harbi, Nafa& Habhab, Wail T.& Fahmi, Ahmad E.. A single-center 4-year experience with 47 pediatric renal transplants : evolving trends. Saudi Journal of Kidney Diseases and Transplantation. 2018. Vol. 29, no. 6, pp.1303-1310.
https://search.emarefa.net/detail/BIM-896379
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 1039-1310
رقم السجل
BIM-896379
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر