Clinical and laboratory profile of renal amyloidosis : a single-center experience
المؤلفون المشاركون
Kute, Vivek B.
Shah, Pankaj R.
Patel, Himanshu V.
Engineer, Divyesh P.
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 29، العدد 5 (31 أكتوبر/تشرين الأول 2018)، ص ص. 1065-1072، 8ص.
الناشر
تاريخ النشر
2018-10-31
دولة النشر
السعودية
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The kidney is the most common organ involved in systemic amyloidosis.
We aimed to study etiology and clinicopathological profile of renal amyloidosis.
This was a retrospective study of 40 consecutive adult patients with biopsy-proven renal amyloidosis evaluated over a period of two years.
Emphasis was given to describing the clinical presentation, renal function, proteinuria, type of amyloidosis, and its etiology.
Mean age of the study cohort was 44 ± 15 years (with a male-to-female ratio of 3:1).
Amyloid A (AA) amyloidosis was the most common type of amyloidosis observed in 72.5% of cases.
Amyloid light chain (AL) amyloidosis accounted for 17.5% of cases, and the rest remained undetermined.
AA amyloidosis had widespread age distribution while AL amyloidosis was confined to those >40 years.
Proteinuria was the most common renal manifestation observed in all patients.
Nephrotic syndrome was seen in 70% of patients.
Mean 24 h proteinuria was 6.4 g.
Renal failure was the second most common manifestation seen in 70% of patients, of whom 21.4% required hemodialysis.
Tuberculosis (TB) accounted for 90% cases of AA amyloidosis.
The most prevalent form was pulmonary TB while the rest accounted for by rheumatoid arthritis and bronchiectasis.
Among patients with TB induced amyloidosis, 61.5% had received adequate treatment for TB in the past.
All patients with AL amyloidosis had nephrotic range proteinuria, five had renal failure out of which two required dialysis.
Cardiac involvement was seen in two patients.
AA amyloidosis was the most common type of renal amyloidosis in the present study and pulmonary TB was the most common etiology
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Engineer, Divyesh P.& Kute, Vivek B.& Patel, Himanshu V.& Shah, Pankaj R.. 2018. Clinical and laboratory profile of renal amyloidosis : a single-center experience. Saudi Journal of Kidney Diseases and Transplantation،Vol. 29, no. 5, pp.1065-1072.
https://search.emarefa.net/detail/BIM-896385
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Engineer, Divyesh P.…[et al.]. Clinical and laboratory profile of renal amyloidosis : a single-center experience. Saudi Journal of Kidney Diseases and Transplantation Vol. 29, no. 5 (Sep. / Oct. 2018), pp.1065-1072.
https://search.emarefa.net/detail/BIM-896385
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Engineer, Divyesh P.& Kute, Vivek B.& Patel, Himanshu V.& Shah, Pankaj R.. Clinical and laboratory profile of renal amyloidosis : a single-center experience. Saudi Journal of Kidney Diseases and Transplantation. 2018. Vol. 29, no. 5, pp.1065-1072.
https://search.emarefa.net/detail/BIM-896385
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Text in English ; abstracts in .
رقم السجل
BIM-896385
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر