Clinicopathological profile of pediatric renal biopsies at a tertiary care hospital, Pakistan
المؤلفون المشاركون
Sadaf, Asim
Khemchand, Moorani N.
Fouzia, Lateef
Asia, Zubair
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 29، العدد 6 (31 ديسمبر/كانون الأول 2018)، ص ص. 1403-1409، 7ص.
الناشر
تاريخ النشر
2018-12-31
دولة النشر
السعودية
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Renal biopsy is an important tool for the diagnosis of acute and chronic glomerular diseases in children.
We aimed to analyze the spectrum of clinical indications and histopathological patterns (HPP) in children who underwent renal biopsy (RB).
This is a retrospective review of case records of 108 renal biopsies carried out from January 2010 to December 2015 at the Pediatric Nephrology Department, National Institute of Child Health Karachi, Pakistan.
RB was performed under Ketamine-Midazolam sedation and real-time ultrasound.
Trucut or monopty biopsy gun was used.
Data obtained included age, gender, clinical indications, biochemical, urinary, and HPP.
Data analyzed by descriptive statistics using SPSS version 20.
Of the total 108 patients who underwent renal biopsy, males were 56.5%.
The mean age of children at biopsy and disease onset was 7.0 ± 4.28 (0.
2-17) and 5.8 ± 4.09 (0.1-15) years, respectively.
Common indications for renal biopsy in primary glomerulonephritis (PGN) were steroid-resistant nephrotic syndrome (SRNS, 36.1%), steroid-dependent nephrotic syndrome (SDNS, 21.3%), and acute nephritic syndrome (ANS) with acute kidney injury (12.0%).
Other indications were systemic lupus erythematosus with nephritis and Henoch-Schonlein purpura among secondary GN.
Histopathological pattern in PGN showed focal segmental glomerulosclerosis (FSGS, 25.9%), minimal change disease (MCD, 22.2%), membranoproliferative GN (MPGN, 12%), and IgM nephropathy (7.4%).
Lupus nephritis (7.4%) was the most common among secondary GN (SGN).
Among 22 SDNS; MCD was found in 16, FSGS in four, and MPGN in two children whereas among 40 SRNS; 10 had MCD, 16 FSGS, and two had MPGN.
We concluded that most common indications of renal biopsy were SRNS followed by SDNS and ANS.
FSGS was the predominant HPP among SRNS and MCD among SDNS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sadaf, Asim& Khemchand, Moorani N.& Fouzia, Lateef& Asia, Zubair. 2018. Clinicopathological profile of pediatric renal biopsies at a tertiary care hospital, Pakistan. Saudi Journal of Kidney Diseases and Transplantation،Vol. 29, no. 6, pp.1403-1409.
https://search.emarefa.net/detail/BIM-896433
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sadaf, Asim…[et al.]. Clinicopathological profile of pediatric renal biopsies at a tertiary care hospital, Pakistan. Saudi Journal of Kidney Diseases and Transplantation Vol. 29, no. 6 (Nov. / Dec. 2018), pp.1403-1409.
https://search.emarefa.net/detail/BIM-896433
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sadaf, Asim& Khemchand, Moorani N.& Fouzia, Lateef& Asia, Zubair. Clinicopathological profile of pediatric renal biopsies at a tertiary care hospital, Pakistan. Saudi Journal of Kidney Diseases and Transplantation. 2018. Vol. 29, no. 6, pp.1403-1409.
https://search.emarefa.net/detail/BIM-896433
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 1408-1409
رقم السجل
BIM-896433
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر