The effect of hypothyroidism on serum irisin level in patients with nondiabetic chronic kidney disease : a pilot study with a cross-sectional design
المؤلفون المشاركون
Patil, Milind Machhindra
Sahoo, Jaya Prakash
Balachandran, Karthik
Kar, Sitanshu Sekhar
Kamalanathan, Sadishkumar
Parameswaran, Sreejith
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 29، العدد 4 (31 أغسطس/آب 2018)، ص ص. 911-915، 5ص.
الناشر
تاريخ النشر
2018-08-31
دولة النشر
السعودية
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Both chronic kidney disease (CKD) and hypothyroidism are associated with decreased serum irisin level.
The presence of hypothyroidism may influence serum irisin level in CKD patients.
The objective of this study was to evaluate the effect of hypothyroidism on serum irisin level in patients with nondiabetic CKD.
Two hundred nondiabetic CKD patients aged between 18 and 65 years with glomerular filtration rate <60 mL/min/1.73 m2 were included in this study.
Forty-three (21.5%) patients had hypothyroidism (overt and subclinical both).
Forty hypothyroid and forty euthyroid CKD patients matched for age and Body Mass Index underwent body composition, biochemical [fasting plasma glucose (FPG) and C-reactive protein], and hormonal (fasting irisin and insulin) evaluation.
Body composition analysis including visceral adipose tissue was done by dual-energy X-ray absorptiometry.
Homeostatic model assessment 2 insulin resistance was calculated from FPG and insulin levels.
The median serum irisin levels were not significantly different between hypothyroid and euthyroid CKD patients [95 (47.74– 261.52) vs.
66 (28.25–224.50) ng/mL, P = 0.30].
There was also no difference in renal function, body composition and other metabolic parameters between the two groups.
To conclude, the presence of hypothyroidism does not alter serum irisin level in patients with nondiabetic CKD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Patil, Milind Machhindra& Parameswaran, Sreejith& Kamalanathan, Sadishkumar& Sahoo, Jaya Prakash& Balachandran, Karthik& Kar, Sitanshu Sekhar. 2018. The effect of hypothyroidism on serum irisin level in patients with nondiabetic chronic kidney disease : a pilot study with a cross-sectional design. Saudi Journal of Kidney Diseases and Transplantation،Vol. 29, no. 4, pp.911-915.
https://search.emarefa.net/detail/BIM-896584
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Patil, Milind Machhindra…[et al.]. The effect of hypothyroidism on serum irisin level in patients with nondiabetic chronic kidney disease : a pilot study with a cross-sectional design. Saudi Journal of Kidney Diseases and Transplantation Vol. 29, no. 4 (Jul. / Aug. 2018), pp.911-915.
https://search.emarefa.net/detail/BIM-896584
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Patil, Milind Machhindra& Parameswaran, Sreejith& Kamalanathan, Sadishkumar& Sahoo, Jaya Prakash& Balachandran, Karthik& Kar, Sitanshu Sekhar. The effect of hypothyroidism on serum irisin level in patients with nondiabetic chronic kidney disease : a pilot study with a cross-sectional design. Saudi Journal of Kidney Diseases and Transplantation. 2018. Vol. 29, no. 4, pp.911-915.
https://search.emarefa.net/detail/BIM-896584
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 914-915
رقم السجل
BIM-896584
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر