Toxoplasma gondii : the prevalence and risk factors in HIV-Infected patients in fars Province, Southern Iran
المؤلفون المشاركون
Arefkhah, Nasir
Afrashteh, Masud
Ridai, Zahrah
Dehghani, Muna
Sarkari, Bahador
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 20، العدد 6 (30 يونيو/حزيران 2018)، ص ص. 1-6، 6ص.
الناشر
تاريخ النشر
2018-06-30
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background: Toxoplasma gondii is a zoonotic protozoan that threatens the health of the people infected with human immunodeficiency virus (HIV).
HIV-positive subjects are at risk of cerebral toxoplasmosis.
Objectives: The current study was designed to find out the seroprevalence of toxoplasmosis in HIV-infected individuals in Fars province, in the South of Iran.
Methods: This cross-sectional study was performed on 251 HIV-infected individuals referred to Shiraz HIV/AIDS Research Center in Fars province, Southern Iran, in 2016.
Blood samples (5 mL) were collected from each individual and sera as well as buffy coat were isolated from each sample.
Demographic and HIV-associated data were obtained from the patients’ medical records.
Anti-Toxoplasma antibodies (both IgG and IgM) were determined by ELISA, using a commercial kit.
In addition, PCR, targeting a 529 bp gene of T.
gondii was performed on the patients’ buffy coats for detection of Toxoplasma DNA.
Results: Anti-Toxoplasma antibodies were detected in the sera of 42 out of 251 (16.7%) HIV infected patients.
Of these, 39 cases (15.5%) were seropositive only for IgG and 3 (1.2%) were positive only for IgM.
Seropositive subjects mainly belonged to 40 - 49 year age group.
None of the subjects were positive for Toxoplasma DNA when evaluated by the PCR.
No significant associations were found between Toxoplasma seropositivity and gender, age, and CD4+ cell level (P > 0.05).
Conclusions: Findings of this study demonstrated a significant rate of seroprevalence of Toxoplasma in HIV infected subjects in Fars province, Southern Iran.
The seropositive cases are at risk of Toxoplasma reactivation and subsequent cerebral encephalitis.
Treatment and also prevention of toxoplasmosis in HIV positive people should be considered.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Arefkhah, Nasir& Sarkari, Bahador& Afrashteh, Masud& Ridai, Zahrah& Dehghani, Muna. 2018. Toxoplasma gondii : the prevalence and risk factors in HIV-Infected patients in fars Province, Southern Iran. Iranian Red Crescent Medical Journal،Vol. 20, no. 6, pp.1-6.
https://search.emarefa.net/detail/BIM-897333
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Arefkhah, Nasir…[et al.]. Toxoplasma gondii : the prevalence and risk factors in HIV-Infected patients in fars Province, Southern Iran. Iranian Red Crescent Medical Journal Vol. 20, no. 6 (Jun. 2018), pp.1-6.
https://search.emarefa.net/detail/BIM-897333
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Arefkhah, Nasir& Sarkari, Bahador& Afrashteh, Masud& Ridai, Zahrah& Dehghani, Muna. Toxoplasma gondii : the prevalence and risk factors in HIV-Infected patients in fars Province, Southern Iran. Iranian Red Crescent Medical Journal. 2018. Vol. 20, no. 6, pp.1-6.
https://search.emarefa.net/detail/BIM-897333
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 5-6
رقم السجل
BIM-897333
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر