Comparison of the effects of Ca-mg carbonate chewable tablets with calcium carbonate tablets on phosphate binding in patients on hemodialysis taking H2-R blockers
المؤلفون المشاركون
al-Rabadi, Katibah H.
Haddad, Ayham
Hindawi, Mahmud
Bani Yunus, Muhammad Nur Mahmud
al-Maayitah, Mahmud Hammad
المصدر
Journal of the Royal Medical Services
العدد
المجلد 26، العدد 1 (30 إبريل/نيسان 2019)، ص ص. 43-49، 7ص.
الناشر
الخدمات الطبية الملكية الأردنية
تاريخ النشر
2019-04-30
دولة النشر
الأردن
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Objectives: Calcium carbonate/magnesium carbonate (CaCO3/MgCO3) combination chewable tablets may be an attractive alternative phosphate binder to calcium carbonate (CaCO3) tablets with potential advantages of synergistic phosphate binding effect.
The aim of this study is to evaluate the differences between the two phosphate binders on 42 hemodialysis patients who are taking H2-Blockers in terms of serum PO4-3 and Mg+2levels.
Methods: Randomized, controlled, open label study was conducted at the renal /hemodialysis unit of King Hussein Medical Center for six weeks (On May 2018).
After the study was approved, patients who met the inclusion criteria were enrolled and were randomly allocated into an interventional group (Group I) and a control group (Group II).
Follow-up continued for 6 weeks.
The collected data were statistically analyzed using the independent t-test.
Results: A total of 37 hemodialysis patients were finally included in this study.
The mean age was 40.81±2.31 years, 17 subjects (45.95%) were males, and 20 subjects (54.05%) were females.
Despite serum PO4-3 level decreased significantly in group I by -0.39±0.99 mg/dl after replacing CaCO3 tablets by CaCO3/MgCO3 in equivalent dose, the differences between two groups were statistically insignificant (- 0.094±0.213).
But when taking into consideration the incremental cost-effectiveness, the CaCO3/MgCO3 tablets are more cost effective by magnitude of 27.766 JD per week for every 1 mg/dl.
Serum magnesium level increased significantly within group I and between the two groups by +0.55±0.36 mg/dl and +0.430±0.089 mg/dl respectively.
Neither serum cCa+2 nor cCa+2 ×PO4 -3 products were changed significantly either among or between the two groups.
Conclusion: No significant difference was detected between Ca-Mg carbonate chewable tablets and the less expensive Ca carbonate tablets in reducing serum phosphate levels in hemodialysis patients on H2-R blockers
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bani Yunus, Muhammad Nur Mahmud& Haddad, Ayham& al-Rabadi, Katibah H.& Hindawi, Mahmud& al-Maayitah, Mahmud Hammad. 2019. Comparison of the effects of Ca-mg carbonate chewable tablets with calcium carbonate tablets on phosphate binding in patients on hemodialysis taking H2-R blockers. Journal of the Royal Medical Services،Vol. 26, no. 1, pp.43-49.
https://search.emarefa.net/detail/BIM-897580
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bani Yunus, Muhammad Nur Mahmud…[et al.]. Comparison of the effects of Ca-mg carbonate chewable tablets with calcium carbonate tablets on phosphate binding in patients on hemodialysis taking H2-R blockers. Journal of the Royal Medical Services Vol. 26, no. 1 (Apr. 2019), pp.43-49.
https://search.emarefa.net/detail/BIM-897580
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bani Yunus, Muhammad Nur Mahmud& Haddad, Ayham& al-Rabadi, Katibah H.& Hindawi, Mahmud& al-Maayitah, Mahmud Hammad. Comparison of the effects of Ca-mg carbonate chewable tablets with calcium carbonate tablets on phosphate binding in patients on hemodialysis taking H2-R blockers. Journal of the Royal Medical Services. 2019. Vol. 26, no. 1, pp.43-49.
https://search.emarefa.net/detail/BIM-897580
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 49
رقم السجل
BIM-897580
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر