Non-traumatic epistaxis management using celox ® dressing : a randomized clinical trial

الملخص EN

Background : Epistaxis is the most common otolaryngologic emergency.

Objectives : The current study aimed at evaluating the therapeutic effect of the Celox® bandage to manage non - traumatic epistaxis in the emergency department.

Methods : In the current randomized, clinical trial, 150 patients with non - traumatic epistaxis admitted to the emergency department in Imam Reza and Sina hospitals affiliated to Tabriz University of Medical Sciences, Tabriz, Iran, during years 2015-2016.

The patients were randomly divided intotwogroups: group 1 dressing with the Celox® bandandgroup 2 dressing with the anterior nasal tampon.

The convenient sampling method was employed.

Bleeding control (minute), patients’ satisfaction, and lack of rebleeding within the first 24 hours of administration were compared between the two groups.

Results : There was no statistically significant difference between the two groups in terms of demographic variables, vital signs, and paraclinical testing results (P > 0.05).

With respect to the control of bleeding in the first 5 minutes after management, 93.3% of the bleeding was controlled in the Celox®, and 96% of the bleeding was controlled in the anterior tampon groups (P = 0.467).

The satisfaction level of the patients in the Celox® group was greater than that of the tampon group, and the difference was statistically significant (P < 0.001).

Lack of rebleeding within 24 hours after management had the most significant effect on the patient satisfaction [odds ratio (OR) = 3.969].

Conclusions : Based on the results of the current study, there was no significant difference in bleeding control and the success rate between the two groups in the study.

Ease of usage, however, makes Celox® a better alternative to control epistaxis.

Furthermore, the treatment of epistaxis with Celox® leads to higher satisfaction levels.