![](/images/graphics-bg.png)
Tegretol (Carbamazepine) effect on the morphometric assay of liver in female white mice (Mus musculus)
المؤلفون المشاركون
al-Bakri, Nahlah Abd al-Rida
Jabir, Nawar R.
المصدر
Ibn al-Haitham Journal for Pure and Applied Science
العدد
المجلد 31، العدد 3 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-9، 9ص.
الناشر
جامعة بغداد كلية التربية ابن الهيثم
تاريخ النشر
2018-12-31
دولة النشر
العراق
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Carbamazepine (CBZ) is one of many anticonvulsants used to treat trigeminal neuralgia and epilepsy.
Antiepileptic drugs (AED`s) are the second most important class of medications that lead to hepatotoxicity and induced liver injury, this study was conducted to evaluate the effects of CBZ on the liver.
A total of 40 female mice were taken and divided into four groups (A/treated for 14 days, B/ control, C/ treated for 30 days, D/ control), the drug was given as an oral suspension formula 100mg/5ml at dose 20 mg/kg/mouse via gastric gavage daily for 14 and 30 days.
Statistical analysis revealed that there were no significant differences in the white female mice body weight (P>0.05) in the treated group for 14 days as well as the treated group for 30 days, but there were significant differences between the treated groups studied.
Statistical analyses result of liver weight, hepatocytes diameter, central vein and portal vein diameters showed significant differences in the treated group for 14 days (P<0.05) as well as the treated group for 30 days, and there were significant differences between all treated groups studied.
The study concluded that carbamazepine (CBZ) can had no effect on body weight but it can induce several hepatic changes if it used on a short or long terms, therefore, it was advised to take cautions when describing this drug.-
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jabir, Nawar R.& al-Bakri, Nahlah Abd al-Rida. 2018. Tegretol (Carbamazepine) effect on the morphometric assay of liver in female white mice (Mus musculus). Ibn al-Haitham Journal for Pure and Applied Science،Vol. 31, no. 3, pp.1-9.
https://search.emarefa.net/detail/BIM-900614
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jabir, Nawar R.& al-Bakri, Nahlah Abd al-Rida. Tegretol (Carbamazepine) effect on the morphometric assay of liver in female white mice (Mus musculus). Ibn al-Haitham Journal for Pure and Applied Science Vol. 31, no. 3 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-900614
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jabir, Nawar R.& al-Bakri, Nahlah Abd al-Rida. Tegretol (Carbamazepine) effect on the morphometric assay of liver in female white mice (Mus musculus). Ibn al-Haitham Journal for Pure and Applied Science. 2018. Vol. 31, no. 3, pp.1-9.
https://search.emarefa.net/detail/BIM-900614
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 7-8
رقم السجل
BIM-900614
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)