![](/images/graphics-bg.png)
Immuno-histochemical changes triggered by repeated cryptosporidium infection in immunosuppressed mice
المؤلفون المشاركون
Majdi, Muna
Ismail, Musa A. M.
Fahmi, Minnat al-Rahman
Yusuf, Hibah Allah Salah Abd Allah
al-Sayyid, Shayma H.
Mahmud, Suhayr S.
Shalabi, Maisa A.
المصدر
Journal of the Egyptian Society of Parasitology
العدد
المجلد 48، العدد 3 (31 ديسمبر/كانون الأول 2018)، ص ص. 483-492، 10ص.
الناشر
الجمعية المصرية لعلم الطفيليات
تاريخ النشر
2018-12-31
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الموضوعات
الملخص EN
Cancers are increasing at an alarming rate with a potential association between parasitosis and cancer.
This study was conducted on 190 albino mice to evaluate the possible histopathological changes and immunohistochemical alteration in the expression of β-catenin and p53 as markers of cellular proliferation in ileocecal region induced by chronic irritation with Cryptosporidium oocysts.
180 experimentally immunosuppressed mice were divided into five groups, control noninfected, infected with 50 oocysts/mouse once, infected with 500 oocysts/mouse once, repeatedly infected with 50 oocysts/mouse/week and repeatedly infected with 500 oocysts/ mouse/week.
Each group was further subdivided into 3 subgroups according to the date designed for scarification.
10 naïve mice were used as negative control.
Histopathological examination of the ileocecal region showed mild to severe villous atrophy and inflammatory exudation in colonic mucosa.
Mice received high inoculum dose showed significantly severe histopathological changes.
A progressive increase of cytoplasmic labeling of β-catenin without loss of β-catenin membrane labeling was recorded in groups infected once, in repeatedly infected ones; there was loss of β- catenin membrane labeling and progressive increase of the cytoplasmic labeling of β-catenin without nuclear expression of β-catenin or nuclear expression of p53 in all infected groups.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fahmi, Minnat al-Rahman& Yusuf, Hibah Allah Salah Abd Allah& al-Sayyid, Shayma H.& Mahmud, Suhayr S.& Majdi, Muna& Shalabi, Maisa A.…[et al.]. 2018. Immuno-histochemical changes triggered by repeated cryptosporidium infection in immunosuppressed mice. Journal of the Egyptian Society of Parasitology،Vol. 48, no. 3, pp.483-492.
https://search.emarefa.net/detail/BIM-901201
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fahmi, Minnat al-Rahman…[et al.]. Immuno-histochemical changes triggered by repeated cryptosporidium infection in immunosuppressed mice. Journal of the Egyptian Society of Parasitology Vol. 48, no. 3 (Dec. 2018), pp.483-492.
https://search.emarefa.net/detail/BIM-901201
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fahmi, Minnat al-Rahman& Yusuf, Hibah Allah Salah Abd Allah& al-Sayyid, Shayma H.& Mahmud, Suhayr S.& Majdi, Muna& Shalabi, Maisa A.…[et al.]. Immuno-histochemical changes triggered by repeated cryptosporidium infection in immunosuppressed mice. Journal of the Egyptian Society of Parasitology. 2018. Vol. 48, no. 3, pp.483-492.
https://search.emarefa.net/detail/BIM-901201
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes appendix : p. 492
رقم السجل
BIM-901201
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)