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Clinical efficacy of nicotine replacement therapy in the treatment of minor recurrent aphthous stomatitis
المؤلفون المشاركون
Zakariyya, Mayy
al-Mishad, Alya
المصدر
Journal of the Arab Society for Medical Research
العدد
المجلد 13، العدد 2 (31 ديسمبر/كانون الأول 2018)، ص ص. 106-112، 7ص.
الناشر
تاريخ النشر
2018-12-31
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background/aim Recurrent aphthous stomatitis (RAS) is a common and widely recognized disease involving the oral mucous membrane.
Nicotine replacement therapy (NRT) is a dose-dependent safe method for encountering useful effects of nicotine.
This study aimed to evaluate the clinical efficacy of NRT in the treatment of minor RAS.
Materials and methods A total of 50 patients from Oral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University, with active minor RAS lasting for less than 48 h were randomly allocated into two groups (25 each): placebo and nicotine groups.
They were treated with placebo and 2-mg nicotine chewing gum, correspondingly, twice daily for 2 weeks.
All participants were assessed for pain, erythema, and ulcer size sores at 4 and 6 days from baseline.
Frequency of recurrence was evaluated at 1-month, 2-month, and 3-month intervals.
Results Regarding pain and erythema scores, the nicotine group showed lower mean with significant difference after 6 days in comparison with the placebo group.
A lower mean of ulcer size was recorded in the nicotine group, with a significant difference after 4 and 6 days.
A lower mean of recurrence score was recorded in nicotine group, with nonsignificant difference compared with the placebo group.
Conclusion Low-dosage NRT in the form of chewing gum may be considered as an innovative and safe alternate treatment modality for minor RAS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zakariyya, Mayy& al-Mishad, Alya. 2018. Clinical efficacy of nicotine replacement therapy in the treatment of minor recurrent aphthous stomatitis. Journal of the Arab Society for Medical Research،Vol. 13, no. 2, pp.106-112.
https://search.emarefa.net/detail/BIM-901991
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zakariyya, Mayy& al-Mishad, Alya. Clinical efficacy of nicotine replacement therapy in the treatment of minor recurrent aphthous stomatitis. Journal of the Arab Society for Medical Research Vol. 13, no. 2 (Jul. / Dec. 2018), pp.106-112.
https://search.emarefa.net/detail/BIM-901991
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zakariyya, Mayy& al-Mishad, Alya. Clinical efficacy of nicotine replacement therapy in the treatment of minor recurrent aphthous stomatitis. Journal of the Arab Society for Medical Research. 2018. Vol. 13, no. 2, pp.106-112.
https://search.emarefa.net/detail/BIM-901991
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 112
رقم السجل
BIM-901991
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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