Detecting mycoplasma pneumoniae infections in nasopharyngeal specimens from paediatric patients with asthma exacerbations in Baghdad : a polymerase chain reaction–gene based study
المؤلفون المشاركون
Ali, Sad Hasan Muhammad
Janabi, Muhyi Kazim Wannas
Nasir, Nadiyah Aziz
Wahbi, Muhammad
المصدر
The Egyptian Journal of Medical Human Genetics
العدد
المجلد 19، العدد 2 (30 إبريل/نيسان 2018)، ص ص. 117-121، 5ص.
الناشر
الجمعية المصرية للأمراض الوراثية
تاريخ النشر
2018-04-30
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background: Numerous viral infections have triggered acute asthma exacerbations.
Despite the fact that diagnosis of M.
pneumoniae infection is based on sero-prevalence studies but molecular diagnostic techniques, such as PCR, have offered improvements in sensitivity, specificity and rapidity over the latest methods.
Objectives: The aim of this molecular study is to determine the infection rates of M.
pneumoniae in acute asthma exacerbation in a group of Iraqi children from Baghdad and also to examine the correlation of the disease with different variable characteristics and symptoms.
Methods: This study included 94 children between 2 and 13 years old; Fifty in-patient asthmatic children and 44 non-asthmatic children as control group who were out-patients of the same hospital.
Throat and nasal swab samples were taken for DNA extraction and PCR procedures.
Results: PCR results show that 33.3% asthmatic patients were positive for M.
pneumoniae while 66.7% were negative (p < 0.001).
53.8% of M.
pneumonia-positive asthmatic children were 2–5 years while 46.2% were 6–14 years old.
Among asthmatic patients with positive PCR, 30.8% had positive history of seasonal pattern (p = 0.026) and 69.2% have positive family history of atopy (p = 0.05).
Conclusions: Family history of atopy has strong association with asthma (p = 0.005), while factors such as sex, residence, seasonal allergen, animal allergen, passive smoking, mode of delivery or consanguinity has not been associated with asthma.
M.
pneumonia in a respective bulk among pediatric patients with asthma constituted an important risk factor for asthma exacerbation presented as cough and wheezy chest without fever or chest X-ray findings.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Janabi, Muhyi Kazim Wannas& Ali, Sad Hasan Muhammad& Nasir, Nadiyah Aziz& Wahbi, Muhammad. 2018. Detecting mycoplasma pneumoniae infections in nasopharyngeal specimens from paediatric patients with asthma exacerbations in Baghdad : a polymerase chain reaction–gene based study. The Egyptian Journal of Medical Human Genetics،Vol. 19, no. 2, pp.117-121.
https://search.emarefa.net/detail/BIM-905781
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Janabi, Muhyi Kazim Wannas…[et al.]. Detecting mycoplasma pneumoniae infections in nasopharyngeal specimens from paediatric patients with asthma exacerbations in Baghdad : a polymerase chain reaction–gene based study. The Egyptian Journal of Medical Human Genetics Vol. 19, no. 2 (Apr. 2018), pp.117-121.
https://search.emarefa.net/detail/BIM-905781
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Janabi, Muhyi Kazim Wannas& Ali, Sad Hasan Muhammad& Nasir, Nadiyah Aziz& Wahbi, Muhammad. Detecting mycoplasma pneumoniae infections in nasopharyngeal specimens from paediatric patients with asthma exacerbations in Baghdad : a polymerase chain reaction–gene based study. The Egyptian Journal of Medical Human Genetics. 2018. Vol. 19, no. 2, pp.117-121.
https://search.emarefa.net/detail/BIM-905781
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 121
رقم السجل
BIM-905781
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر