Anti-inflammatory activity of Tetragronula species from Indonesia
المؤلفون المشاركون
Abd al-Munim
Sahlan, Muhammad
Devina, Andrea
Pratami, Diah Kartika
Situmorang, Herbert
Farida, Siti
Kusumoputro, Benyamin
Yohda, Masafumi
Farid, Ahmad
Gozan, Misri
Ledyawati, Mia
المصدر
Saudi Journal of Biological Sciences
العدد
المجلد 26، العدد 7 (30 نوفمبر/تشرين الثاني 2019)، ص ص. 1531-1538، 8ص.
الناشر
تاريخ النشر
2019-11-30
دولة النشر
السعودية
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
Anti-inflammatory drugs inhibit inflammation, particularly those classified as nonsteroidal anti-inflammatory drugs (NSAIDs).
Several studies have reported that propolis has both anti-ulcerogenic and anti-inflammatory effects.
In this study, we investigated the bioactive compound and in vivo anti-inflammatory properties of both smooth and rough propolis from Tetragronula sp.
To further identify anti-inflammatory markers in propolis, LC-MS/MS was used, and results were analyzed by Mass Lynx 4.1.
Rough and smooth propolis of Tetragonula sp.
were microcapsulated with maltodextrin and arabic gum.
Propolis microcapsules at dose 25–200 mg/kg were applied for carrageenan-induced rat’s paw-inflammation model.
Data were analyzed by one-way ANOVA and Kruskal–Wallis statistical tests.
LC-MS/MS experiments identified seven anti-inflammatory compounds, including [6]-dehydrogingerdione, alpha-tocopherol succinate, adhyperforin, 6-epiangustifolin, deoxypodophyllotoxin, kurarinone, and xanthoxyletin.
Our results indicated that smooth propolis at 50 mg/kg inhibited inflammation to the greatest extent, followed by rough propolis at a dose of 25 mg/kg.
SPM and RPM with the dose of 25 mg/kg had inflammatory inhibition value of 62.24% and 58.12%, respectively, which is comparable with the value 70.26% of sodium diclofenac with the dose of 135 mg/kg.
This study suggests that propolis has the potential candidate to develop as a non-steroid anti-inflammatory drug.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sahlan, Muhammad& Devina, Andrea& Pratami, Diah Kartika& Situmorang, Herbert& Farida, Siti& Abd al-Munim…[et al.]. 2019. Anti-inflammatory activity of Tetragronula species from Indonesia. Saudi Journal of Biological Sciences،Vol. 26, no. 7, pp.1531-1538.
https://search.emarefa.net/detail/BIM-910169
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sahlan, Muhammad…[et al.]. Anti-inflammatory activity of Tetragronula species from Indonesia. Saudi Journal of Biological Sciences Vol. 26, no. 7 (Nov. 2019), pp.1531-1538.
https://search.emarefa.net/detail/BIM-910169
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sahlan, Muhammad& Devina, Andrea& Pratami, Diah Kartika& Situmorang, Herbert& Farida, Siti& Abd al-Munim…[et al.]. Anti-inflammatory activity of Tetragronula species from Indonesia. Saudi Journal of Biological Sciences. 2019. Vol. 26, no. 7, pp.1531-1538.
https://search.emarefa.net/detail/BIM-910169
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 1537-1538
رقم السجل
BIM-910169
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر