In vivo pharmacological investigation of Monotheca buxifolia and Bosea amherstiana using animal models
المؤلفون المشاركون
Khan, Shahid Allah
Rahman, Khaista
Khan, Wasim Allah
Ansari, Muhammad Javed
Hasan, Said
Linfang, Huang
Anjum, Sayyid Ishtiaq
Qamar, Rabiah
Man, Shad
Shah, Aishah Halim
Nabi, Ghulam
Ahmad, Iftikhar
Ahmad, Bashir
المصدر
Saudi Journal of Biological Sciences
العدد
المجلد 26، العدد 7 (30 نوفمبر/تشرين الثاني 2019)، ص ص. 1602-1606، 5ص.
الناشر
تاريخ النشر
2019-11-30
دولة النشر
السعودية
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Experimental based evidence suggests that most of the medicinal plants possess wide-ranging pharmacological and biological activities that may possibly use in treatment of inflammation-related diseases.
The current study was aimed to explore the acute toxicity, analgesic, sedative and antipyretic activities of Monotheca buxifolia and Bosea amherstiana in mices.
In vivo experimental models were used in this study.
Acute toxicity was evaluated for 24 h’ interval at concentration of 500, 1000, 1500 and 2000 mg/kg.
The analgesic activity was estimated by acetic acid induced writhing test.
White wood apparatus enclosed in stainless steel was used for sedative experiment and antipyretic activity was evaluated in brewer’s yeast induced hyperthermic at 50, 100 and 150 mg/kg i.p.
Both plants were found safe at all tested doses.
Monotheca buxifolia and Bosea amherstiana dose-dependently reduced abdominal constrictions in mice.
Both plants exhibited significant (P < 0.0001) sedative effects in dose of 50, 150 and 150 mg/kg.
Both plants markedly (P < 0.0001) reduced yeast induced hyperthermia.
The inhibitions were dose-dependent and remained significant up to five hours of administration.
These investigational results have linked a pharmacological indication for the traditional claim of the drugs to be used as an anti-inflammatory, analgesics and antipyretic agents.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hasan, Said& Ahmad, Bashir& Khan, Shahid Allah& Linfang, Huang& Anjum, Sayyid Ishtiaq& Ansari, Muhammad Javed…[et al.]. 2019. In vivo pharmacological investigation of Monotheca buxifolia and Bosea amherstiana using animal models. Saudi Journal of Biological Sciences،Vol. 26, no. 7, pp.1602-1606.
https://search.emarefa.net/detail/BIM-910181
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hasan, Said…[et al.]. In vivo pharmacological investigation of Monotheca buxifolia and Bosea amherstiana using animal models. Saudi Journal of Biological Sciences Vol. 26, no. 7 (Nov. 2019), pp.1602-1606.
https://search.emarefa.net/detail/BIM-910181
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hasan, Said& Ahmad, Bashir& Khan, Shahid Allah& Linfang, Huang& Anjum, Sayyid Ishtiaq& Ansari, Muhammad Javed…[et al.]. In vivo pharmacological investigation of Monotheca buxifolia and Bosea amherstiana using animal models. Saudi Journal of Biological Sciences. 2019. Vol. 26, no. 7, pp.1602-1606.
https://search.emarefa.net/detail/BIM-910181
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 1606
رقم السجل
BIM-910181
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر