Synthesis characterization of some new heterocyclic compounds containing1, 3-oxazepine ring

الملخص EN

In this work a series of 1, 3-oxazepine derivatives have been synthesized throughout two steps.

First step synthesis of imines derivatives (A1-A7) via the condensation reaction of 4-hydroxy benzaldehyde with different substituted amines by using catalytic amount of glacial acetic acid, while the second step involves reactions of the prepared imines (A1-A7) via maleic anhydride by [2+5] cycloaddition in dry benzene and refluxing it to produce 1, 3 - oxazepine - 4, 7 - dione derivatives (A1m-A7m) respectively.

The prepared compounds were characterized by C.H.N.S micro analysis, some physical properties and spectral methods (IR , H1-NMR).