The adjunctive role of application of Mitomycin C intraoeratively with posterior transverse Iaser cordotomy in treatment of bilateral abductor vocal fold paralysis
المؤلفون المشاركون
Majdi, Sabri
Kamal, Ihab
Fawwaz, Samiyah
al-Makhzangi, Ali
Hijazi, Muna
المصدر
Egyptian Journal of Ear, Nose, Throat and Allied Sciences
العدد
المجلد 10، العدد 1 (30 يونيو/حزيران 2009)، ص ص. 8-12، 5ص.
الناشر
الجمعية المصرية للأذن و الأنف و الحنجرة و العلوم المشتركة
تاريخ النشر
2009-06-30
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Bilateral abductor vocal fold paralysis (BAVFP) is a common complication following thyroidectomy.
In those patients whose airway is compromised by the paralyzed vocal folds, tracheostomy is emergently indicated, which is, though life-saving, a stigmatizing mishap with significant impact on quality of life.
A significant proportion of afflicted patients recover recurrent laryngeal nerve function 6-12 months after the onset, and thus may get rid of the tracheostomy. However, patients who do not recover vocal fold mobility always seek to become independent of the tracheostomy tube. Dennis and Kashima (1989) have devised Posterior Transverse CO2 Laser Cordotomy (PTLC) in order to relief the obstruction at the posterior glottis.
Variable results for this procedure have been reported.
Granulation tissue with subsequent scar formation may be a cause for the varying results.
Mitomycin C (MMC), an anti-mitotic chemotherapeutic agent has been shown to reduce granulation and scar tissue formation in multiple studies using animal models in which airway scarring is induced.
MMC has also shown significant prevention of re-stenosis following surgical correction of laryngotracheal stenosis.
We report, for the first time, a case-control series of 23 patients with post-thyroidectomy BAVFP who have undergone PTLC.
The study group (12) had MMC adjuvant application during PTLC.
Thirteen patients had a tracheostomy prior to inclusion.
Three outcomes of the intervention were compared in the study and control groups: decannulation rate (for tracheostomized patients), dyspnea symptom scale (DSS) change for non-tracheostomized patients, and voice quality.
DSS was the only outcome that showed a statistically significant difference between the study and control groups.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Majdi, Sabri& Kamal, Ihab& Fawwaz, Samiyah& al-Makhzangi, Ali& Hijazi, Muna. 2009. The adjunctive role of application of Mitomycin C intraoeratively with posterior transverse Iaser cordotomy in treatment of bilateral abductor vocal fold paralysis. Egyptian Journal of Ear, Nose, Throat and Allied Sciences،Vol. 10, no. 1, pp.8-12.
https://search.emarefa.net/detail/BIM-94602
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Majdi, Sabri…[et al.]. The adjunctive role of application of Mitomycin C intraoeratively with posterior transverse Iaser cordotomy in treatment of bilateral abductor vocal fold paralysis. Egyptian Journal of Ear, Nose, Throat and Allied Sciences Vol. 10, no. 1 (Jun. 2009), pp.8-12.
https://search.emarefa.net/detail/BIM-94602
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Majdi, Sabri& Kamal, Ihab& Fawwaz, Samiyah& al-Makhzangi, Ali& Hijazi, Muna. The adjunctive role of application of Mitomycin C intraoeratively with posterior transverse Iaser cordotomy in treatment of bilateral abductor vocal fold paralysis. Egyptian Journal of Ear, Nose, Throat and Allied Sciences. 2009. Vol. 10, no. 1, pp.8-12.
https://search.emarefa.net/detail/BIM-94602
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 12
رقم السجل
BIM-94602
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر