Some anti-diabetic properties of Prosopis farcta extracts in alloxan induced diabetic in adult rats
العناوين الأخرى
بعض الصفات المضادة للسكري لمستخلصات Prosopis farcta في الجرذان البالغة المستحدث فيها السكري بالألوكسان
المؤلفون المشاركون
Muhammad, Ismail Hasan
Kaki, Ismail Salih
Farimani, Mahdi Moridi
المصدر
Iraqi Journal of Veterinary Sciences
العدد
المجلد 34، العدد 1 (30 يونيو/حزيران 2020)، ص ص. 109-113، 5ص.
الناشر
جامعة الموصل كلية الطب البيطري
تاريخ النشر
2020-06-30
دولة النشر
العراق
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Prosopis farcta is belonged to Mimosaceae family, commonly known as mesquite.
It was chosen to investigate their effect on α-glucosidase inhibitory activity (in-vitro), serum glucose and liver functions.
Roots, fruits, and leaves of P.
farcta, were extracted by n-hexane, ethyl acetate, and methanol.
α-glucosidase inhibition was analyzed by using ELISA technique then half maximal inhibitory concentration IC50 was found.
The blood glucose levels were determined with a glucose analyzer model.
The serum alkaline phosphatase (ALP), Alanine transaminase (ALT), aspartate aminotransferase (AST) and serum total bilirubin (TB) were estimated by using the Cobas diagnostic kit with a fully automated chemical analyzer.
Diabetes was done by a single dose of 120 mg alloxan/kg b.w with subcutaneously injection.
Ethyl acetate extracts of P.
farcta showed the higher α-glucosidase inhibitory activity, and the best one was root extract.
Treatments of the alloxan-induced diabetes rats were done by daily oral administration of different concentrations with P.
farcta extracts of ethyl acetate for 28 days and the dose 200 mg/kg BW was the effective one.
The root extract was the best one for reduction of serum glucose followed by leaves then fruits.
Administration of root extract of P.
farcta showed a decrease in the levels of ALP and TB in alloxan-induced diabetes rats.
The fruit extract of P.
farcta showed decreasing in the level of ALP in alloxan-induced diabetes rats.
In conclusion, the P.
farcta extracts for ethyl acetate have properties of hypoglycemic effect as well as improving some parameters related with diabetic complications of liver functions.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Muhammad, Ismail Hasan& Kaki, Ismail Salih& Farimani, Mahdi Moridi. 2020. Some anti-diabetic properties of Prosopis farcta extracts in alloxan induced diabetic in adult rats. Iraqi Journal of Veterinary Sciences،Vol. 34, no. 1, pp.109-113.
https://search.emarefa.net/detail/BIM-948795
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Muhammad, Ismail Hasan…[et al.]. Some anti-diabetic properties of Prosopis farcta extracts in alloxan induced diabetic in adult rats. Iraqi Journal of Veterinary Sciences Vol. 34, no. 1 (2020), pp.109-113.
https://search.emarefa.net/detail/BIM-948795
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Muhammad, Ismail Hasan& Kaki, Ismail Salih& Farimani, Mahdi Moridi. Some anti-diabetic properties of Prosopis farcta extracts in alloxan induced diabetic in adult rats. Iraqi Journal of Veterinary Sciences. 2020. Vol. 34, no. 1, pp.109-113.
https://search.emarefa.net/detail/BIM-948795
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 113
رقم السجل
BIM-948795
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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