Synthesis, characterization of silver nanoparticles using nigella sativa seeds and study their effects on the serum lipid profile and DNA damage on the rats’ blood treated with hydrogen peroxide
العناوين الأخرى
تصنيع، و توصيف جسيمات الفضة النانوية المصنعة باستعمال حبة السوداء و دراسة تأثيرها على مستوى الدهون في المصل الدم و تلف الحمض النووي في دم الجرذان المعالجة ببيروكسيد الهيدروجين
المؤلفون المشاركون
Ali, Zaynab Sattar
Khudayr, Khalisah Kazim
المصدر
Iraqi Journal of Veterinary Medicine
العدد
المجلد 43، العدد 2 (31 ديسمبر/كانون الأول 2019)، ص ص. 23-37، 15ص.
الناشر
تاريخ النشر
2019-12-31
دولة النشر
العراق
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
This study was aimed to produce silver nanoparticles using aqueous extract of Nigella sativa, also to investigate the effects of green synthesized Nigella sativa seeds silver nanoparticles on dyslipidemia and DNA fragmentation in hydrogen peroxide-exposed rats.
The produced Nigella sativa seeds silver nanoparticles were characterized through Ultraviolet-Visible spectroscopy, Fourier-transform infrared spectroscopy, X-ray powder diffraction (XRD) style, and Scanning Electron Microscope was used to investigate the morphology and size of synthesized Nigella sativa seeds silver nanoparticles.
Forty adults male rats were randomly and equally divided into five groups and daily had been remedying for two months as followings: G1 group (Control), G2 group, rats in this group were received tap water containing 1% H2O2, animals in G3 and G4 groups were injected IP Nigella sativa seeds silver nanoparticles 25 and 50 mg/kg B.W., respectively, and received ordinary tap water containing 1% H2O2 , and G5 group, animals in this group were injected IP Nigella sativa seeds extract 50 mg/kg B.W.
and received ordinary tap water containing 1% H2O2.
Blood samples collected after one and two months of the experiment from each animal for DNA fragmentation measurements and serum estimated lipid profile.The results receded a case of dyslipidemia, as well significant elevation in DNA damage in G4 and G2 groups The results also confirmed the hypolipidemic and cytoprotective effect of Nigella sativa seeds extract (G5 group) and silver nanoparticles as25mg/kg B.W (group G3) clarified by correction of dyslipidemia, alongside significant alleviation in DNA damage.
In conclusion, the results in the current study effectsof Nigella sativa seeds silver nanoparticles at high dose and documents the ameliorative effect of Nigella sativaseeds extract and Nigella sativa seeds silver nanoparticles on lipid profile and DNA damage
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ali, Zaynab Sattar& Khudayr, Khalisah Kazim. 2019. Synthesis, characterization of silver nanoparticles using nigella sativa seeds and study their effects on the serum lipid profile and DNA damage on the rats’ blood treated with hydrogen peroxide. Iraqi Journal of Veterinary Medicine،Vol. 43, no. 2, pp.23-37.
https://search.emarefa.net/detail/BIM-952748
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ali, Zaynab Sattar& Khudayr, Khalisah Kazim. Synthesis, characterization of silver nanoparticles using nigella sativa seeds and study their effects on the serum lipid profile and DNA damage on the rats’ blood treated with hydrogen peroxide. Iraqi Journal of Veterinary Medicine Vol. 43, no. 2 (2019), pp.23-37.
https://search.emarefa.net/detail/BIM-952748
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ali, Zaynab Sattar& Khudayr, Khalisah Kazim. Synthesis, characterization of silver nanoparticles using nigella sativa seeds and study their effects on the serum lipid profile and DNA damage on the rats’ blood treated with hydrogen peroxide. Iraqi Journal of Veterinary Medicine. 2019. Vol. 43, no. 2, pp.23-37.
https://search.emarefa.net/detail/BIM-952748
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Text in English ; abstracts in English and Arabic.
رقم السجل
BIM-952748
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر