Microbial causes of urinary tract infection and its sensitivity to antibiotics at Heevi Pediatric Teaching Hospital Duhok City

الملخص EN

Background : Urinary tract infection (UTI) refers to the presence of microbial pathogens within the urinary tract, and it is usually classified by the site of infection as the bladder (cystitis), kidney (pyelonephritis), or urine (bacteriuria).

Objectives : The objectives of this study were to determine the etiological bacterial pathogens of UTIs and to identify antibiotic sensitivity patterns of pathogens isolated among age groups of children.

Materials and Methods : In this cross-sectional study, a random sample of the local registry of Heevi pediatric hospital of thepatients who were diagnosed with UTI and were sent for antibiotic sensitivity between August 2018 and July 2019 was taken for analysis.

Seven hundred and twenty‑two patients were included in the present study whose ages ranged from birth to more than 10 years.

Results : The study showed that 22.

8 % and 20.

6 % of the patients were in > 3–5 and 7-10 years of age and majority were females (66.

5 %).

The study revealed that 56.

2 % of the patients had different pathogens, and Escherichia coli was the most common pathogen in the diagnosed patients with UTI.

The pathogens had different frequency in the urine samples.

Most of the cultures were sensitive to gentamycin (23.

4 %), amikacin (27.

6%), and norfloxacin (25.

4 %).

The most resistant cultures were toward trimethoprim (31.

2%), cephalothin (32.

6%), and cefixime (21.

6%).

The study showed that E.

coli was prevalent pathogen in all age groups.

The study did show that common antibiotics were not statistically significantly different between male and female patients, including gentamycin (P = 0.

145), amoxicillin (P = 0.

304), and norfloxacin (P = 0.

407).

The common antibiotics were more prevalent in > 3–5 years group, including gentamycin; amoxicillin; and norfloxacin.

Conclusion: This study finding showed that E.

coli isolates were the predominant pathogens and showed increasing sensitivity pattern to antimicrobial gentamycin, amikacin, and norfloxacin.