The ameliorative effect of Methanolic red carrot extract and vitamin e against cadmium-induced testicular toxicity in rats
المؤلفون المشاركون
Abd al-Wahhab, Ahmad
Abd al-Raziq, Abd al-Raziq H.
Hasanayn, Kamil M. A.
Abd al-Badi, Wala I. E.
Mahmud, Ahmad A. J.
المصدر
Journal of Veterinary Medical Research
العدد
المجلد 26، العدد 2 (31 ديسمبر/كانون الأول 2019)، ص ص. 247-257، 11ص.
الناشر
جامعة بني سويف كلية الطب البيطري
تاريخ النشر
2019-12-31
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الموضوعات
الملخص EN
The current study aimed to investigate the effects of methanolic red carrot extract (MRCE) against cadmium intoxication on testis of adult Wister albino male rats.
For that purpose, forty eight Wister albino male rats were randomly divided into four groups (12 rats per group).
Group 1 (normal control), animals received corn oil.
Group 2 (cadmium group), animals received cadmium chloride (CdCl2) at a dose of (5 mg / kg BW).
Group 3 (cadmium and Vit.
E group), animals received vitamin E at a dose of (400mg / kg BW) and CdCl2at a dose of (5 mg / kg BW).
Group 4 (cadmium & red carrot extract, animals received methanol: water red carrot extract (1 : 1) at a dose of 400 mg / kg and CdCl2 at a dose of (5 mg / kg BW).
All rats were received their corresponding treatment orally by gastric gavage daily for 4 weeks.
Result of organ weight analysis in Cd –exposed rats showed a decrease in testes weight.
On the contrary, MRCE and vitamin E prophylactic co-treatments with cadmium showed significant increase in testis weights in comparison to cadmium group (P < 0.05).
Moreover, sperm concentrations were reduced markedly with cadmium while they were upturned greatly after prophylactic co-treatment with either MRCE or vitamin E (P < 0.05).
Moreover, cadmium induced a significant increase in testicular malondialdehyde (MDA) and significant decrease of total antioxidant capacity (TAC) but both MRCE and vitamin E supplementation succeeded markedly to produce a significant reduction in testicular MDA and noticeable increase of TAC level.
Thus, MRCE and vitamin E could be considered optimal prophylactic treatments to protect the testis of rats from cadmium intoxication.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hasanayn, Kamil M. A.& Abd al-Wahhab, Ahmad& Abd al-Raziq, Abd al-Raziq H.& Abd al-Badi, Wala I. E.& Mahmud, Ahmad A. J.. 2019. The ameliorative effect of Methanolic red carrot extract and vitamin e against cadmium-induced testicular toxicity in rats. Journal of Veterinary Medical Research،Vol. 26, no. 2, pp.247-257.
https://search.emarefa.net/detail/BIM-979226
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hasanayn, Kamil M. A.…[et al.]. The ameliorative effect of Methanolic red carrot extract and vitamin e against cadmium-induced testicular toxicity in rats. Journal of Veterinary Medical Research Vol. 26, no. 2 (2019), pp.247-257.
https://search.emarefa.net/detail/BIM-979226
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hasanayn, Kamil M. A.& Abd al-Wahhab, Ahmad& Abd al-Raziq, Abd al-Raziq H.& Abd al-Badi, Wala I. E.& Mahmud, Ahmad A. J.. The ameliorative effect of Methanolic red carrot extract and vitamin e against cadmium-induced testicular toxicity in rats. Journal of Veterinary Medical Research. 2019. Vol. 26, no. 2, pp.247-257.
https://search.emarefa.net/detail/BIM-979226
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 254-257
رقم السجل
BIM-979226
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر