Evaluation of the predictive value of serum C-reactive protein and procalcitonin levels in early detection of anastomotic leakage after gastrointestinal surgery
المؤلفون المشاركون
al-Najjar, Mahmud
Abu Ali, Mustafa
Shaban, Hamdi
al-Karaki, Muhammad Ahmad
المصدر
Suez Canal University Medical Journal
العدد
المجلد 23، العدد 1 (30 يونيو/حزيران 2020)، ص ص. 30-40، 11ص.
الناشر
تاريخ النشر
2020-06-30
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : Anastomotic leak (AL) after gastrointestinal surgery is a serious postoperative complication that leads to significant morbidity and mortality.
Objective : To evaluate the role of sequential postoperative serum determinations of C-reactive protein (CRP) and Procalcitonin (PCT) in the identification and prediction of anastomotic leakage after gastrointestinal surgery and to describe the kinetics of PCT and CRP after surgery and their relative usefulness for the early detection of anastomotic leaks after gastrointestinal surgery.
Patients and Methods: This study is a clinical prospective randomized observational analytical cross-sectional study conducted in the elective and emergency surgery theaters of the department of general surgery at Suez Canal university hospital from Jan 2015 to Jan 2016 on 45 patients who underwent small bowel, colonic and rectal surgery with resection and primary anastomosis.
The data was collected using a questionnaire and lab results.
Results: In our study, 22.2% of study patients developed anastomotic leakage, 48.9 % of the studied population was between the ages of (46–60) (range 18-72 years), and 62.2 % of the study populations were female.
Both biochemical markers were elevated in patients with anastomotic leakage at day2, 3, and 4 and showed slightly similar curves, percentages but the upper hand was for PCT than CRP in the point of early detection and in the much more sensitive and more specific.
The Pearson correlation with fistula was more powerful for CRP than for PCT.
Conclusion: Patients with PCT greater than 0.65mg/dL and CRP greater than 21 mg/dL on Day4, even in the absence of clinical signs, are not permitted to leave the hospital and a diagnostic work-up for sepsis (lung, urinary tract, intra-abdominal, or wound) is actively pursued.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Karaki, Muhammad Ahmad& al-Najjar, Mahmud& Abu Ali, Mustafa& Shaban, Hamdi. 2020. Evaluation of the predictive value of serum C-reactive protein and procalcitonin levels in early detection of anastomotic leakage after gastrointestinal surgery. Suez Canal University Medical Journal،Vol. 23, no. 1, pp.30-40.
https://search.emarefa.net/detail/BIM-980531
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Karaki, Muhammad Ahmad…[et al.]. Evaluation of the predictive value of serum C-reactive protein and procalcitonin levels in early detection of anastomotic leakage after gastrointestinal surgery. Suez Canal University Medical Journal Vol. 23, no. 1 (2020), pp.30-40.
https://search.emarefa.net/detail/BIM-980531
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Karaki, Muhammad Ahmad& al-Najjar, Mahmud& Abu Ali, Mustafa& Shaban, Hamdi. Evaluation of the predictive value of serum C-reactive protein and procalcitonin levels in early detection of anastomotic leakage after gastrointestinal surgery. Suez Canal University Medical Journal. 2020. Vol. 23, no. 1, pp.30-40.
https://search.emarefa.net/detail/BIM-980531
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 41-42
رقم السجل
BIM-980531
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر