Hematological and biochemical studies on cattle theileriosis with special reference to its effect on some antioxidant agents

الملخص EN

The goal of the present study was to investigate the effect of cattle theileriosis on general health condition and some haematological and biochemical parameters specially Ascorbic acid and vitamin E as a model for studying the blood oxidative status in parasitized cattle .

Atotal number 140 caws were subjected to the study their age ranged from 6 months to over 5 years belonged to some private farms in different localities at Kalubeia governorate ,all animals were examined clinically showed 46suspected cases (30.7%)which had signs of theileria infection and the laboratory parasitological examination confirmed the infection with theileria annulata the rest of the animals were proved healthy and used as control .The affected caws had high body temperature (40-41C),enlarged superficial lymphnodes ,anorexia ,congestion of mucous membranes and increased respiratory rates .Inadvances cases of the disease signs of anemia ,general weakness in addition to presence of ticks on animal body .

The study cleared that animals at age of 6 months to one year have a higher rate of infection (33.3%)followed by the age of 1-3 years (30%),3-5 years (23.3%) and finally over 5 years (8%).

Hematological investigation of the affected animals proved presence of anemia represented by significant decrease of total erythrocytic count ,haemoglobin concentration and packed cell volume .The leukogram showed that there was leukocytosis as aresult of neutrophilia ,lymphocytosis and monocytosis .

The result of evaluation study of chain –breaking antioxidants vitamin E and ascorbic acid revealed significant decrease of these vitamins in diseased animals compaired with control .

Concerning with biochemical changes the infected animals showed significant decrease in total protein, albumin and glucose level .Activities of serum transaminases (AST,ALT)total bilirubin ,urea and creatinine showed significant increase .