Attenuation of Acute Lung Inflammation and Injury by Whole Body Cooling in a Rat Heatstroke Model
المؤلفون المشاركون
Cheng, Ruei-Tang
Yang, Hsi-Hsing
Lin, Mao- Tsun
Chang, Ching-Ping
المصدر
العدد
المجلد 2009، العدد 2009 (31 ديسمبر/كانون الأول 2009)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2009-11-17
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Whole body cooling is the current therapy of choice for heatstroke because the therapeutic agents are not available.
In this study, we assessed the effects of whole body cooling on several indices of acute lung inflammation and injury which might occur during heatstroke.
Anesthetized rats were randomized into the following groups and given (a) no treatment or (b) whole body cooling immediately after onset of heatstroke.
As compared with the normothermic controls, the untreated heatstroke rats had higher levels of pleural exudates volume and polymorphonuclear cell numbers, lung myloperoxidase activity and inducible nitric oxide synthase expression, histologic lung injury score, and bronchoalveolar proinflammatory cytokines and glutamate, and PaCO2.
In contrast, the values of mean arterial pressure, heart rate, PaO2, pH, and blood HCO3− were all significantly lower during heatstroke.
The acute lung inflammation and injury and electrolyte imbalance that occurred during heatstroke were significantly reduced by whole body cooling.
In conclusion, we identified heat-induced acute lung inflammation and injury and electrolyte imbalance could be ameliorated by whole body cooling.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Hsi-Hsing& Chang, Ching-Ping& Cheng, Ruei-Tang& Lin, Mao- Tsun. 2009. Attenuation of Acute Lung Inflammation and Injury by Whole Body Cooling in a Rat Heatstroke Model. BioMed Research International،Vol. 2009, no. 2009, pp.1-9.
https://search.emarefa.net/detail/BIM-988443
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Hsi-Hsing…[et al.]. Attenuation of Acute Lung Inflammation and Injury by Whole Body Cooling in a Rat Heatstroke Model. BioMed Research International No. 2009 (2009), pp.1-9.
https://search.emarefa.net/detail/BIM-988443
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Hsi-Hsing& Chang, Ching-Ping& Cheng, Ruei-Tang& Lin, Mao- Tsun. Attenuation of Acute Lung Inflammation and Injury by Whole Body Cooling in a Rat Heatstroke Model. BioMed Research International. 2009. Vol. 2009, no. 2009, pp.1-9.
https://search.emarefa.net/detail/BIM-988443
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-988443
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر