The Vectorial Potential of Lutzomyia (Nyssomyia)‎ intermedia and Lutzomyia (N.)‎ whitmani in the Transmission of Leishmania (V.)‎ braziliensis Can Also Be Related to Proteins Attaching

الملخص EN

We read with great interest the report by Soares et al.

[1] on the potential of Leishmania (Viannia) braziliensis to attach to the midgut of the sand flies Lutzomyia (N.) whitmani and Lutzomyia (N.) intermedia.

This manuscript assesses relevant information concerning the biomolecular phenomena between Leishmania promastigotes and the midgut of Lutzomyia species that act as vectors of American Cutaneous Leishmaniasis (ACL).

However, it is necessary to comment that the basis of these physiological processes is not directly driven by glycolipid lipophosphoglycan (LPG) only.

Other L.

(V.) braziliensis promastigotes surface components, as proteins, can also be implicated in many steps of the midgut attachment.