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Separation of Normal and Premalignant Cervical Epithelial Cells Using Confocal Light Absorption and Scattering Spectroscopic Microscopy Ex Vivo
المؤلفون المشاركون
Wu, Hao
Wang, Cheng
Ping, Bo
Yang, Ling
Shi, Da-Ren
Liu, Wen-Tao
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-10-10
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Confocal light absorption and scattering spectroscopic (CLASS) microscopy can detect changes in biochemicals and the morphology of cells.
It is therefore used to detect high-grade cervical squamous intraepithelial lesion (HSIL) cells in the diagnosis of premalignant cervical lesions.
Forty cervical samples from women with abnormal Pap smear test results were collected, and twenty cases were diagnosed as HSIL; the rest were normal or low-grade cervical squamous intraepithelial lesion (LSIL).
The enlarged and condensed nuclei of HSIL cells as viewed under CLASS microscopy were much brighter and bigger than those of non-HSIL cells.
Cytological elastic scattered light data was then collected at wavelengths between 400 and 1000 nm.
Between 600 nm to 800 nm, the relative elastic scattered light intensity of HSIL cells was higher than that of the non-HSIL.
Relative intensity peaks occurred at 700 nm and 800 nm.
CLASS sensitivity and specificity results for HSIL and non-HSIL compared to cytology diagnoses were 80% and 90%, respectively.
This study demonstrated that CLASS microscopy could effectively detect cervical precancerous lesions.
Further study will verify this conclusion before the method is used in clinic for early detection of cervical cancer.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Ling& Liu, Wen-Tao& Wu, Hao& Wang, Cheng& Ping, Bo& Shi, Da-Ren. 2011. Separation of Normal and Premalignant Cervical Epithelial Cells Using Confocal Light Absorption and Scattering Spectroscopic Microscopy Ex Vivo. BioMed Research International،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-989935
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Ling…[et al.]. Separation of Normal and Premalignant Cervical Epithelial Cells Using Confocal Light Absorption and Scattering Spectroscopic Microscopy Ex Vivo. BioMed Research International No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-989935
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Ling& Liu, Wen-Tao& Wu, Hao& Wang, Cheng& Ping, Bo& Shi, Da-Ren. Separation of Normal and Premalignant Cervical Epithelial Cells Using Confocal Light Absorption and Scattering Spectroscopic Microscopy Ex Vivo. BioMed Research International. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-989935
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-989935
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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