Contribution of the Residual Body in the Spatial Organization of Toxoplasma gondii Tachyzoites within the Parasitophorous Vacuole

المؤلفون المشاركون

Mondragón, M.
Mondragón-González, S. L.
González del Carmen, M.
González, S.
Mondragón, R.
Cesbron, M. F.
Muñiz-Hernández, Saé
Mercier, C.

المصدر

BioMed Research International

العدد

المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-11، 11ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2011-11-28

دولة النشر

مصر

عدد الصفحات

11

التخصصات الرئيسية

الطب البشري

الملخص EN

Toxoplasma gondii proliferates and organizes within a parasitophorous vacuole in rosettes around a residual body and is surrounded by a membranous nanotubular network whose function remains unclear.

Here, we characterized structure and function of the residual body in intracellular tachyzoites of the RH strain.

Our data showed the residual body as a body limited by a membrane formed during proliferation of tachyzoites probably through the secretion of components and a pinching event of the membrane at the posterior end.

It contributes in the intravacuolar parasite organization by the membrane connection between the tachyzoites posterior end and the residual body membrane to give place to the rosette conformation.

Radial distribution of parasites in rosettes favors an efficient exteriorization.

Absence of the network and presence of atypical residual bodies in a ΔGRA2-HXGPRT knock-out mutant affected the intravacuolar organization of tachyzoites and their exteriorization.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Muñiz-Hernández, Saé& González del Carmen, M.& Mondragón, M.& Mercier, C.& Cesbron, M. F.& Mondragón-González, S. L.…[et al.]. 2011. Contribution of the Residual Body in the Spatial Organization of Toxoplasma gondii Tachyzoites within the Parasitophorous Vacuole. BioMed Research International،Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-990129

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Muñiz-Hernández, Saé…[et al.]. Contribution of the Residual Body in the Spatial Organization of Toxoplasma gondii Tachyzoites within the Parasitophorous Vacuole. BioMed Research International No. 2011 (2011), pp.1-11.
https://search.emarefa.net/detail/BIM-990129

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Muñiz-Hernández, Saé& González del Carmen, M.& Mondragón, M.& Mercier, C.& Cesbron, M. F.& Mondragón-González, S. L.…[et al.]. Contribution of the Residual Body in the Spatial Organization of Toxoplasma gondii Tachyzoites within the Parasitophorous Vacuole. BioMed Research International. 2011. Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-990129

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-990129