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Antiobesity and Hypoglycaemic Effects of Aqueous Extract of Ibervillea sonorae in Mice Fed a High-Fat Diet with Fructose
المؤلفون المشاركون
Garduño-Siciliano, Leticia
Paniagua-Castro, Norma
Galaviz-Hernández, Carlos
Rivera-Ramírez, Fabiola
Escalona-Cardoso, Gerardo N.
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-11-17
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Obesity, type II diabetes, and hyperlipidaemia, which frequently coexist and are strongly associated with oxidative stress, increase the risk of cardiovascular disease.
An increase in carbohydrate intake, especially of fructose, and a high-fat diet are both factors that contribute to the development of these metabolic disorders.
In recent studies carried out in diabetic rats, authors reported that Ibervillea sonorae had hypoglycaemic activity; saponins and monoglycerides present in the plant could be responsible for the effects observed.
In the present study, we determined the effects of an aqueous I.
sonorae extract on a murine model of obesity and hyperglycaemia, induced by a high-calorie diet, and the relationship of these effects with hepatic oxidation.
A high-fat diet over a period of 8 weeks induced weight gain in the mice and increased triglycerides and blood glucose levels.
Simultaneous treatment with I.
sonorae aqueous extracts, at doses of 100, 200, and 400 mg/kg, decreased triglycerides and glycaemia levels, prevented an increase in body weight in a dose-dependent manner, and decreased hepatic lipid oxidation at a dose of 200 mg/kg.
These data suggest that the aqueous extract from I.
sonorae root prevents obesity, dyslipidaemia, and hyperglycaemia induced by a hypercaloric diet; however, high doses may induce toxicity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rivera-Ramírez, Fabiola& Escalona-Cardoso, Gerardo N.& Garduño-Siciliano, Leticia& Galaviz-Hernández, Carlos& Paniagua-Castro, Norma. 2011. Antiobesity and Hypoglycaemic Effects of Aqueous Extract of Ibervillea sonorae in Mice Fed a High-Fat Diet with Fructose. BioMed Research International،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-990421
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rivera-Ramírez, Fabiola…[et al.]. Antiobesity and Hypoglycaemic Effects of Aqueous Extract of Ibervillea sonorae in Mice Fed a High-Fat Diet with Fructose. BioMed Research International No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-990421
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rivera-Ramírez, Fabiola& Escalona-Cardoso, Gerardo N.& Garduño-Siciliano, Leticia& Galaviz-Hernández, Carlos& Paniagua-Castro, Norma. Antiobesity and Hypoglycaemic Effects of Aqueous Extract of Ibervillea sonorae in Mice Fed a High-Fat Diet with Fructose. BioMed Research International. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-990421
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-990421
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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