Increased Placental Glucose Transport Rates in Pregnant Mice Carrying Fetuses with Targeted Disruption of Their Placental-Specific Igf2 Transcripts Are Not Associated with Raised Circulating Glucose Concentrations
المؤلفون المشاركون
Evans, Mark L.
Dunger, David B.
Wingate, Dianne L.
Petry, Clive J.
Reik, Wolf
Ong, Ken K.
Constância, Miguel
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-01-20
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
At the beginning of the third week of pregnancy, mouse fetuses with targeted disruption of their paternally-transmitted insulin-like growth factor 2 gene placental-specific transcripts have growth-restricted placentas but normal body weights due to upregulated placental nutrient transport.
We assessed whether increased placental glucose transport rates were associated with raised maternal glucose concentrations by performing intraperitoneal glucose tolerance tests (ipGTT) in pregnant mice carrying knockout pups and comparing them with mice carrying genotype-matched phenotypically wild type pups.
Mean ± SD body weights of affected pups were 95 ± 8% of control values at e16 and 73 ± 7% at e18.
There were no differences in areas under the maternal ipGTT curves at either e16 (mean ± SD being 99.0 ± 9.1% of control values; P=.9) or e18 (91.4 ± 13.4%; P=.3), suggesting that effects on transplacental glucose transport in these mice are not mediated through changes in maternal glucose concentrations.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Petry, Clive J.& Evans, Mark L.& Wingate, Dianne L.& Ong, Ken K.& Reik, Wolf& Constância, Miguel…[et al.]. 2011. Increased Placental Glucose Transport Rates in Pregnant Mice Carrying Fetuses with Targeted Disruption of Their Placental-Specific Igf2 Transcripts Are Not Associated with Raised Circulating Glucose Concentrations. Journal of Diabetes Research،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-990618
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Petry, Clive J.…[et al.]. Increased Placental Glucose Transport Rates in Pregnant Mice Carrying Fetuses with Targeted Disruption of Their Placental-Specific Igf2 Transcripts Are Not Associated with Raised Circulating Glucose Concentrations. Journal of Diabetes Research No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-990618
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Petry, Clive J.& Evans, Mark L.& Wingate, Dianne L.& Ong, Ken K.& Reik, Wolf& Constância, Miguel…[et al.]. Increased Placental Glucose Transport Rates in Pregnant Mice Carrying Fetuses with Targeted Disruption of Their Placental-Specific Igf2 Transcripts Are Not Associated with Raised Circulating Glucose Concentrations. Journal of Diabetes Research. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-990618
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-990618
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر