Effect of Deep Brain Stimulation on Parkinson's Nonmotor Symptoms following Unilateral DBS: A Pilot Study
المؤلفون المشاركون
Kim, Sung K.
Ul Haq, Ihtsham
Jacobson, Charles E.
Resnick, Andrew S.
Okun, Michael S.
Fernandez, Hubert H.
Dai, Yunfeng
Wu, Samuel S.
Malaty, Irene A.
Foote, Kelly D.
Hwynn, Nelson
Oyama, Genko
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-12-19
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Parkinson’s disease (PD) management has traditionally focused largely on motor symptoms.
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) and globus pallidus internus (GPi) are effective treatments for motor symptoms.
Nonmotor symptoms (NMSs) may also profoundly affect the quality of life.
The purpose of this pilot study was to evaluate NMS changes pre- and post-DBS utilizing two recently developed questionnaires.
Methods.
NMS-Q (questionnaire) and NMS-S (scale) were administered to PD patients before/after unilateral DBS (STN/GPi targets).
Results.
Ten PD patients (9 STN implants, 1 GPi implant) were included.
The three most frequent NMS symptoms identified utilizing NMS-Q in pre-surgical patients were gastrointestinal (100%), sleep (100%), and urinary (90%).
NMS sleep subscore significantly decreased (−1.6 points ± 1.8, P=0.03).
The three most frequent NMS symptoms identified in pre-surgical patients using NMS-S were gastrointestinal (90%), mood (80%), and cardiovascular (80%).
The largest mean decrease of NMS scores was seen in miscellaneous symptoms (pain, anosmia, weight change, and sweating) (−7 points ± 8.7), and cardiovascular/falls (−1.9, P=0.02).
Conclusion.
Non-motor symptoms improved on two separate questionnaires following unilateral DBS for PD.
Future studies are needed to confirm these findings and determine their clinical significance as well as to examine the strengths/weaknesses of each questionnaire/scale.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hwynn, Nelson& Ul Haq, Ihtsham& Malaty, Irene A.& Resnick, Andrew S.& Dai, Yunfeng& Foote, Kelly D.…[et al.]. 2011. Effect of Deep Brain Stimulation on Parkinson's Nonmotor Symptoms following Unilateral DBS: A Pilot Study. Parkinson’s Disease،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-991066
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hwynn, Nelson…[et al.]. Effect of Deep Brain Stimulation on Parkinson's Nonmotor Symptoms following Unilateral DBS: A Pilot Study. Parkinson’s Disease No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-991066
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hwynn, Nelson& Ul Haq, Ihtsham& Malaty, Irene A.& Resnick, Andrew S.& Dai, Yunfeng& Foote, Kelly D.…[et al.]. Effect of Deep Brain Stimulation on Parkinson's Nonmotor Symptoms following Unilateral DBS: A Pilot Study. Parkinson’s Disease. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-991066
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-991066
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر