Vaxjo: A Web-Based Vaccine Adjuvant Database and Its Application for Analysis of Vaccine Adjuvants and Their Uses in Vaccine Development
المؤلفون المشاركون
Sayers, Samantha
Xiang, Zuoshuang
He, Yongqun Oliver
Ulysse, Guerlain
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-03-13
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Vaccine adjuvants are compounds that enhance host immune responses to co-administered antigens in vaccines.
Vaxjo is a web-based central database and analysis system that curates, stores, and analyzes vaccine adjuvants and their usages in vaccine development.
Basic information of a vaccine adjuvant stored in Vaxjo includes adjuvant name, components, structure, appearance, storage, preparation, function, safety, and vaccines that use this adjuvant.
Reliable references are curated and cited.
Bioinformatics scripts are developed and used to link vaccine adjuvants to different adjuvanted vaccines stored in the general VIOLIN vaccine database.
Presently, 103 vaccine adjuvants have been curated in Vaxjo.
Among these adjuvants, 98 have been used in 384 vaccines stored in VIOLIN against over 81 pathogens, cancers, or allergies.
All these vaccine adjuvants are categorized and analyzed based on adjuvant types, pathogens used, and vaccine types.
As a use case study of vaccine adjuvants in infectious disease vaccines, the adjuvants used in Brucella vaccines are specifically analyzed.
A user-friendly web query and visualization interface is developed for interactive vaccine adjuvant search.
To support data exchange, the information of vaccine adjuvants is stored in the Vaccine Ontology (VO) in the Web Ontology Language (OWL) format.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sayers, Samantha& Ulysse, Guerlain& Xiang, Zuoshuang& He, Yongqun Oliver. 2012. Vaxjo: A Web-Based Vaccine Adjuvant Database and Its Application for Analysis of Vaccine Adjuvants and Their Uses in Vaccine Development. BioMed Research International،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-991925
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sayers, Samantha…[et al.]. Vaxjo: A Web-Based Vaccine Adjuvant Database and Its Application for Analysis of Vaccine Adjuvants and Their Uses in Vaccine Development. BioMed Research International No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-991925
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sayers, Samantha& Ulysse, Guerlain& Xiang, Zuoshuang& He, Yongqun Oliver. Vaxjo: A Web-Based Vaccine Adjuvant Database and Its Application for Analysis of Vaccine Adjuvants and Their Uses in Vaccine Development. BioMed Research International. 2012. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-991925
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-991925
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر