![](/images/graphics-bg.png)
Effect of Colic Vein Ligature in Rats with Loperamide-Induced Constipation
المؤلفون المشاركون
Cavallari, Giuseppe
Bianchi, Elisa
Piras, Gian Luca
Guidetti, Elena
Nardo, Bruno
Neri, Flavia
Tsivian, Matvey
Pariali, Milena
Cevenini, Monica
Aldini, Rita
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-05-08
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Medical treatment in chronic constipation is not always successful.
Surgery is indicated in unresponsive selected severe cases.
This study presents the distal venous colic ligation in rat as a novel surgical approach.
Materials and Methods.
16 rats (study group) were evaluated in 3 phases of 6 days each: A (normal conditions), B (loperamide-induced constipation), and C (colic vein legation) and compared with rats treated in phase C with PEG 4,000 (control group).
Blood biochemical and physiological parameters, daily fecal water content (FWC), and histological analysis were performed in all study phases.
Results.
No biochemical and physiological parameters changes were observed.
FWC decreased in phase B and increased in phase C in both groups with a grow up to 2.3-fold in study group compared to control (P<0.0001).
Moreover, in study group, a high number of colonic goblet cells were detected (phase C versus phase B: P<0.001) while no differences were registered in control.
Conclusion.
By ligature of the colic vein in constipated rats, an increase in FWC and goblet cells higher than in PEG treated rats was detected.
The described surgical procedure appeared effective, simple, and safe; further studies in animal models, however, are necessary to assess its clinical applicability.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Neri, Flavia& Cavallari, Giuseppe& Tsivian, Matvey& Bianchi, Elisa& Aldini, Rita& Cevenini, Monica…[et al.]. 2012. Effect of Colic Vein Ligature in Rats with Loperamide-Induced Constipation. BioMed Research International،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-991945
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Neri, Flavia…[et al.]. Effect of Colic Vein Ligature in Rats with Loperamide-Induced Constipation. BioMed Research International No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-991945
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Neri, Flavia& Cavallari, Giuseppe& Tsivian, Matvey& Bianchi, Elisa& Aldini, Rita& Cevenini, Monica…[et al.]. Effect of Colic Vein Ligature in Rats with Loperamide-Induced Constipation. BioMed Research International. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-991945
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-991945
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)